RA CAPITAL MANAGEMENT, L.P. - 18 Oct 2022 Form 4 Insider Report for 89bio, Inc. (ETNB)

Role: Director, 10%+ Owner
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P.
Issuer symbol: ETNB
Transactions as of: 18 Oct 2022
Net transactions value: +$8,971,469
Form type: 4
Filing time: 20 Oct 2022, 17:28:57 UTC
Previous filing: 19 Oct 2022
Next filing: 24 Oct 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ETNB	Common Stock	Purchase	$8,971,469	+1,172,741	+15%	$7.65	8,955,410	18 Oct 2022	See Footnotes	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	8,620,046 shares are held directly by the RA Capital Healthcare Fund, L.P (the "Fund") and 335,364 shares are held directly by RA Capital Nexus Fund , L.P. (the "Nexus Fund").
F2	RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

Content

8,620,046 shares are held directly by the RA Capital Healthcare Fund, L.P (the "Fund") and 335,364 shares are held directly by RA Capital Nexus Fund , L.P. (the "Nexus Fund").

RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.