Laura Lee Sandler - 01 Jul 2025 Form 4 Insider Report for Oruka Therapeutics, Inc. (ORKA)

Role: Chief Operating Officer
Signature: /s/ Paul Quinlan, as attorney-in-fact for Laura Sandler
Issuer symbol: ORKA
Transactions as of: 01 Jul 2025
Net transactions value: $0
Form type: 4
Filing time: 01 Jul 2025, 21:26:04 UTC
Next filing: 02 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Sandler Laura Lee	Chief Operating Officer	C/O ORUKA THERAPEUTICS, INC., 855 OAK GROVE AVE., SUITE 100, MENLO PARK	/s/ Paul Quinlan, as attorney-in-fact for Laura Sandler	01 Jul 2025	0002075401

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ORKA	Employee Stock Option (right to buy)	Award	$0	+25,000		$0.000000	25,000	01 Jul 2025	Common Stock	25,000	$11.80	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The option vests as to 1/4 of the underlying shares on July 1, 2026, and as to 1/48 of the underlying shares monthly thereafter.