Laura Lee Sandler - 01 Jul 2025 Form 3 Insider Report for Oruka Therapeutics, Inc. (ORKA)

Role: Chief Operating Officer
Signature: /s/ Paul Quinlan, as attorney-in-fact for Laura Sandler
Issuer symbol: ORKA
Transactions as of: 01 Jul 2025
Net transactions value: $0
Form type: 3
Filing time: 01 Jul 2025, 21:21:50 UTC
Next filing: 02 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Sandler Laura Lee	Chief Operating Officer	C/O ORUKA THERAPEUTICS, INC., 855 OAK GROVE AVE., SUITE 100, MENLO PARK	/s/ Paul Quinlan, as attorney-in-fact for Laura Sandler	01 Jul 2025	0002075401

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	ORKA	Common Stock						213,084	01 Jul 2025	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	ORKA	Warrant (right to buy)							01 Jul 2025	Common Stock	99,996	$7.80	Direct	F1
holding	ORKA	Employee Stock Option (right to buy)							01 Jul 2025	Common Stock	137,500	$12.50	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This warrant represents a right to purchase 99,996 shares of the Issuer's common stock, one quarter of which will vest on April 3, 2025, with the remaining three quarters vesting in equal monthly installments over the following three years, subject to the Reporting Person's continued service to the Issuer on each such vesting date.
F2	The option vests as to 1/48 of the underlying shares monthly from January 1, 2025.