| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | TWST | Common Stock | Sale | -$151K | -1.41K | -74.39% | $106.93 | 486 | Aug 12, 2021 | Direct | |
| transaction | TWST | Common Stock | Sale | -$4.39M | -41K | -34.3% | $106.98 | 78.6K | Aug 12, 2021 | By Keith L. Crandell Trust | F6 |
| transaction | TWST | Common Stock | Sale | -$275K | -2.56K | -3.25% | $107.56 | 76K | Aug 12, 2021 | By Keith L. Crandell Trust | F7 |
| transaction | TWST | Common Stock | Other | $0 | -286K | -39.41% | $0.00 | 440K | Feb 11, 2021 | By Arch Venture Fund VII, L.P. | F1, F2, F4, F5 |
| transaction | TWST | Common Stock | Other | $0 | +14.6K | +17.61% | $0.00 | 97.3K | Feb 11, 2021 | By Keith L. Crandell Trust | F1, F5 |
| transaction | TWST | Common Stock | Other | $0 | -114K | -39.4% | $0.00 | 175K | Feb 11, 2021 | By ARCH Venture Fund VIII Overage, L.P. | F1, F3, F4, F5 |
| transaction | TWST | Common Stock | Other | $0 | +1 | +0% | $0.00 | 97.3K | Feb 11, 2021 | By Keith L. Crandell Trust | F1, F5 |
| transaction | TWST | Common Stock | Other | $0 | -215K | -48.79% | $0.00 | 226K | May 13, 2021 | By ARCH Venture Fund VII, L.P. | F1, F2, F4, F5 |
| transaction | TWST | Common Stock | Other | $0 | +10.9K | +11.23% | $0.00 | 108K | May 13, 2021 | By Keith L. Crandell Trust | F1, F5 |
| transaction | TWST | Common Stock | Other | $0 | -85.2K | -48.79% | $0.00 | 89.4K | May 13, 2021 | By ARCH Venture Fund VIII Overage, L.P. | F1, F3, F4, F5 |
| transaction | TWST | Common Stock | Other | $0 | +1 | +0% | $0.00 | 108K | May 13, 2021 | By Keith L. Crandell Trust | F1, F5 |
| transaction | TWST | Common Stock | Other | $0 | -226K | -100% | $0.00* | 0 | May 19, 2021 | By ARCH Venture Fund VII, L.P. | F1, F2, F4, F5 |
| transaction | TWST | Common Stock | Other | $0 | +11.5K | +10.6% | $0.00 | 120K | May 19, 2021 | By Keith L. Crandell Trust | F1, F5 |
| transaction | TWST | Common Stock | Other | $0 | -89.4K | -100% | $0.00* | 0 | May 19, 2021 | By ARCH Venture Fund VIII Overage, L.P. | F1, F3, F4, F5 |
| transaction | TWST | Common Stock | Other | $0 | +1 | +0% | $0.00 | 120K | May 19, 2021 | By Keith L. Crandell Trust | F1, F5 |
| Id | Content |
|---|---|
| F1 | Pro-rata distribution of Common Stock held by a limited partnership to its partners for no consideration. |
| F2 | The shares were directly held by ARCH Venture Fund VII, L.P. ("ARCH Fund VII"). The sole general partner of ARCH Fund VII is ARCH Venture Partners VII, L.P. ("ARCH Partners VII"), which may be deemed to be the beneficial owner of the shares held by ARCH Fund VII. The sole general partner of ARCH Partners VII is ARCH Venture Partners VII, LLC ("ARCH VII LLC"), which may be deemed to be the beneficial owner of the shares held by ARCH Fund VII. ARCH Partners VII and ARCH VII LLC disclaim beneficial ownership of such shares, except to the extent of any pecuniary interest therein. |
| F3 | The shares were directly held by ARCH Venture Fund VIII Overage, L.P. ("ARCH Overage"). The sole general partner of ARCH Overage is ARCH Venture Partners VIII, LLC ("ARCH VIII LLC"), which may be deemed to be the beneficial owner of the shares held by ARCH Overage. ARCH VIII LLC disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein. |
| F4 | Keith Crandell is a managing director of ARCH VII LLC and ARCH VIII LLC, and may be deemed to beneficially own the shares held by ARCH Fund VII and ARCH Overage. Mr. Crandell disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein. |
| F5 | Change in form of ownership of shares previously reported as beneficially owned by the reporting person. |
| F6 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $106.39 to $107.37. The reporting person undertakes to provide to TWST, any security holder of TWST, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (6) and (7) to this Form 4. |
| F7 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $107.405 to $107.70. |