Perceptive Advisors Llc - May 24, 2021 Form 4 Insider Report for Nautilus Biotechnology, Inc. (NAUT)

Role: Former Director
Signature: /s/ Joseph Edelman - for Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager, By: Joseph Edelman, its managing member
Stock symbol: NAUT
Transactions as of: May 24, 2021
Transactions value $: $55,070,983
Form type: 4
Date filed: 6/11/2021, 05:45 PM
Previous filing: May 24, 2021
Next filing: Jun 1, 2021

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	NAUT	Common Stock	Purchase	$71K	+7.06K	+1.44%	$10.05	497K	May 24, 2021	Direct
transaction	NAUT	Common Stock	Purchase	$55M	+5.5M	+1106.56%	$10.00	6M	Jun 9, 2021	See Footnote	F1
transaction	NAUT	Common Stock	Other		+2.91M	+48.59%		8.91M	Jun 9, 2021	See Footnote	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Perceptive Advisors Llc is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may continue.

Explanation of Responses:

Id	Content
F1	The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.
F2	Acquired pursuant to the business combination by and among ARYA Sciences Acquisition Corp III, Mako Merger Sub, Inc. and Nautilus Biotechnology, Inc. ("Old Nautilus") in exchange for shares of Old Nautilus previously held by the Master Fund.

Content

The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Acquired pursuant to the business combination by and among ARYA Sciences Acquisition Corp III, Mako Merger Sub, Inc. and Nautilus Biotechnology, Inc. ("Old Nautilus") in exchange for shares of Old Nautilus previously held by the Master Fund.