| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| DEBBANE RAYMOND | Director | 2445 TECHNOLOGY FOREST BLVD., 11TH FLOOR, THE WOODLANDS | /s/ Raymond Debbane | 25 Feb 2026 | 0001053890 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | LXRX | Common Stock | Purchase | $147,000 | +100,000 | +5.5% | $1.47 | 1,904,186 | 23 Feb 2026 | Direct | |
| holding | LXRX | Common Stock | 1,538,462 | 23 Feb 2026 | By Avicenna Life Sci Master Fund LP and related parties | ||||||
| holding | LXRX | Common Stock | 7,362,368 | 23 Feb 2026 | By Invus Public Equities, L.P. and related parties | ||||||
| holding | LXRX | Common Stock | 5,451,204 | 23 Feb 2026 | By Invus US Partners, LLC and related parties | ||||||
| holding | LXRX | Common Stock | 35,402,689 | 23 Feb 2026 | By Invus, L.P. and related parties |