Rohan Palekar - 01 Aug 2025 Form 4 Insider Report for 89bio, Inc. (ETNB)

Role: Chief Executive Officer, Director
Signature: /s/ Ryan A. Murr, as attorney-in-fact for Rohan Palekar
Issuer symbol: ETNB
Transactions as of: 01 Aug 2025
Net transactions value: -$511,458
Form type: 4
Filing time: 05 Aug 2025, 20:06:54 UTC
Previous filing: 13 Jun 2025
Next filing: 30 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
PALEKAR ROHAN	Chief Executive Officer, Director	C/O 89BIO, INC., 655 MONTGOMERY STREET, SUITE 1500, SAN FRANCISCO	/s/ Ryan A. Murr, as attorney-in-fact for Rohan Palekar	05 Aug 2025	0001423327

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ETNB	Common Stock	Tax liability	$511,458	-55,836	-6.5%	$9.16	808,070	01 Aug 2025	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These shares were withheld from the vesting of restricted stock units to cover the estimated tax withholding obligation.
F2	Includes an aggregate of 1,666 shares acquired by the Reporting Person under the Issuer's 2019 Employee Stock Purchase Plan on June 30, 2025.