Gil M. Labrucherie - 07 Feb 2025 Form 4 Insider Report for Septerna, Inc. (SEPN)

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	SEPN	Stock Option (Right to Buy)	Award	$0	+222,000		$0.000000	222,000	07 Feb 2025	Common Stock	222,000	$13.09	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Id	Content
F1	25% of the shares underlying this option will vest on January 6, 2026, and the remaining 75% of the shares underlying this option will vest in thirty-six substantially equal monthly installments thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.