Parkman Healthcare Partners LLC - 06 Oct 2025 Form 3 Insider Report for SPRUCE BIOSCIENCES, INC. (SPRB)

Role: 10%+ Owner
Signature: Parkman Healthcare Partners LLC, By: /s/ Gregory Martinez, Chief Investment Officer
Issuer symbol: SPRB
Transactions as of: 06 Oct 2025
Net transactions value: $0
Form type: 3
Filing time: 08 Oct 2025, 20:53:52 UTC
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Parkman Healthcare Partners LLC	10%+ Owner	700 CANAL STREET, STAMFORD	Parkman Healthcare Partners LLC, By: /s/ Gregory Martinez, Chief Investment Officer	08 Oct 2025	0001777015

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	SPRB	Common Stock, par value $0.0001 per share						1,051	06 Oct 2025	See footnote	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The amount reported represents the Reporting Persons' pecuniary interest held through an investment in private funds. Each Reporting Person disclaims beneficial ownership in the securities reported on this Form 3 except to the extent of its or his pecuniary interest, if any, therein, and this report shall not be deemed to be an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

Content

The amount reported represents the Reporting Persons' pecuniary interest held through an investment in private funds. Each Reporting Person disclaims beneficial ownership in the securities reported on this Form 3 except to the extent of its or his pecuniary interest, if any, therein, and this report shall not be deemed to be an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

Remarks:

A subsequent Form 3 will be filed for Gregory Martinez once CIK codes are received.