| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Gayer Charles K | President and CCO | 4505 EMPEROR BLVD., SUITE 200, DURHAM | /s/ Alane P. Barnes, by power of attorney | 23 Dec 2025 | 0001800110 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | BCRX | Common Stock | Tax liability | $85,045 | -11,477 | -1.3% | $7.41 | 878,350 | 19 Dec 2025 | Direct | F1 |
| transaction | BCRX | Common Stock | Options Exercise | $45,537 | +14,142 | +1.6% | $3.22 | 892,492 | 22 Dec 2025 | Direct | |
| transaction | BCRX | Common Stock | Options Exercise | $50,859 | +10,091 | +1.1% | $5.04 | 902,583 | 22 Dec 2025 | Direct | |
| transaction | BCRX | Common Stock | Options Exercise | $275,500 | +50,000 | +5.5% | $5.51 | 952,583 | 22 Dec 2025 | Direct |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | BCRX | Emp. Stock Option (Right to Buy) | Options Exercise | $0 | -14,142 | -100% | $0.000000 | 0 | 22 Dec 2025 | Common Stock | 14,142 | $3.22 | Direct | F2 |
| transaction | BCRX | Emp. Stock Option (Right to Buy) | Options Exercise | $0 | -10,091 | -37% | $0.000000 | 17,409 | 22 Dec 2025 | Common Stock | 10,091 | $5.04 | Direct | F2 |
| transaction | BCRX | Emp. Stock Option (Right to Buy) | Options Exercise | $0 | -50,000 | -100% | $0.000000 | 0 | 22 Dec 2025 | Common Stock | 50,000 | $5.51 | Direct | F2 |
| Id | Content |
|---|---|
| F1 | Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted restricted stock units. This transaction does not represent a sale by the reporting person. |
| F2 | The option grant became exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant. |