Charles K. Gayer - 12 Dec 2025 Form 4 Insider Report for BIOCRYST PHARMACEUTICALS INC (BCRX)

Role: President and CCO
Signature: /s/ Alane P. Barnes, by power of attorney
Issuer symbol: BCRX
Transactions as of: 12 Dec 2025
Net transactions value: -$61,930
Form type: 4
Filing time: 16 Dec 2025, 16:21:18 UTC
Previous filing: 23 Dec 2024
Next filing: 19 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Gayer Charles K	President and CCO	4505 EMPEROR BLVD., SUITE 200, DURHAM	/s/ Alane P. Barnes, by power of attorney	16 Dec 2025	0001800110

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BCRX	Common Stock	Tax liability	$61,930	-8,181	-1.9%	$7.57	418,827	12 Dec 2025	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted restricted stock units. This transaction does not represent a sale by the reporting person.