| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Kewalramani Reshma | CEO & President, Director | C/O VERTEX PHARMACEUTICALS INCORPORATED, 50 NORTHERN AVENUE, BOSTON | /s/ Christiana Stevenson, Attorney-in-Fact | 19 Feb 2026 | 0001735944 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRTX | Common Stock | Award | $0 | +16,326 | +12% | $0.000000 | 149,813 | 17 Feb 2026 | Direct | F1 |
| transaction | VRTX | Common Stock | Tax liability | $3,170,498 | -6,554 | -4.4% | $483.75 | 143,259 | 17 Feb 2026 | Direct |
| Id | Content |
|---|---|
| F1 | Restricted stock unit award that vests in installments beginning on February 20, 2027. |