Charles F. Wagner Jr. - 06 Jan 2026 Form 4 Insider Report for VERTEX PHARMACEUTICALS INC / MA (VRTX)

Signature
/s/ Christiana Stevenson, Attorney-in-Fact
Issuer symbol
VRTX
Transactions as of
06 Jan 2026
Net transactions value
-$2,589,082
Form type
4
Filing time
08 Jan 2026, 16:04:39 UTC
Previous filing
05 Dec 2025
Next filing
26 Jan 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
WAGNER CHARLES F JR EVP, CO & FO C/O VERTEX PHARMACEUTICALS INCORPORATED, 50 NORTHERN AVENUE, BOSTON /s/ Christiana Stevenson, Attorney-in-Fact 08 Jan 2026 0001223348

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction VRTX Common Stock Options Exercise $1,805,170 +9,532 +25% $189.38 47,257 06 Jan 2026 Direct
transaction VRTX Common Stock Sale $4,394,252 -9,532 -20% $461.00 37,725 06 Jan 2026 Direct F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction VRTX Stock Option (Right to Buy) Options Exercise $0 -9,532 -100% $0.000000 0 06 Jan 2026 Common Stock 9,532 $189.38 Direct F2
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Transaction made pursuant to Mr. Wagner's company approved trading plan under Rule 10b5-1, which was entered into on 5/09/2025.
F2 Fully vested.