Charles F. Wagner Jr. - 03 Dec 2025 Form 4 Insider Report for VERTEX PHARMACEUTICALS INC / MA (VRTX)

Signature
/s/ Christiana Stevenson, Attorney-in-Fact
Issuer symbol
VRTX
Transactions as of
03 Dec 2025
Net transactions value
-$6,384,000
Form type
4
Filing time
05 Dec 2025, 16:16:48 UTC
Previous filing
12 Jun 2025
Next filing
08 Jan 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
WAGNER CHARLES F JR EVP, CO & FO C/O VERTEX PHARMACEUTICALS INCORPORATED, 50 NORTHERN AVENUE, BOSTON /s/ Christiana Stevenson, Attorney-in-Fact 05 Dec 2025 0001223348

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction VRTX Common Stock Sale $3,157,000 -7,000 -14% $451.00 44,725 03 Dec 2025 Direct F1
transaction VRTX Common Stock Sale $3,227,000 -7,000 -16% $461.00 37,725 03 Dec 2025 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Transaction made pursuant to Mr. Wagner's company approved trading plan under Rule 10b5-1, which was entered into on 5/9/2025.