-
Signature
-
/s/ Christiana Stevenson, Attorney-in-Fact
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Stock symbol
-
VRTX
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Transactions as of
-
Nov 13, 2025
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Transactions value $
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-$25,799,237
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Form type
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4
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Date filed
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11/17/2025, 04:12 PM
Reporting Owners (1)
| Name |
Relationship |
Address |
Signature |
Signature date |
CIK |
| LEIDEN JEFFREY M |
Executive Chairman, Director |
C/O VERTEX PHARMACEUTICALS INCORPORATED, 50 NORTHERN AVENUE, BOSTON |
/s/ Christiana Stevenson, Attorney-in-Fact |
2025-11-17 |
0001242825 |
Transactions Table
| Type |
Sym |
Class |
Transaction |
Value $ |
Shares |
Change % |
* Price $ |
Shares After |
Date |
Ownership |
Footnotes |
| transaction |
VRTX |
Common Stock |
Options Exercise |
$1.79M |
+19.7K |
+81.94% |
$91.05 |
43.7K |
Nov 13, 2025 |
Direct |
|
| transaction |
VRTX |
Common Stock |
Sale |
-$8.16M |
-18.5K |
-42.38% |
$440.22 |
25.2K |
Nov 13, 2025 |
Direct |
F1, F2, F3 |
| transaction |
VRTX |
Common Stock |
Sale |
-$512K |
-1.16K |
-4.61% |
$441.05 |
24K |
Nov 13, 2025 |
Direct |
F1, F2, F4 |
| transaction |
VRTX |
Common Stock |
Options Exercise |
$1.26M |
+13.8K |
+57.58% |
$91.05 |
37.9K |
Nov 14, 2025 |
Direct |
|
| transaction |
VRTX |
Common Stock |
Options Exercise |
$3.44M |
+39.8K |
+105.04% |
$86.52 |
77.6K |
Nov 14, 2025 |
Direct |
|
| transaction |
VRTX |
Common Stock |
Sale |
-$14.2M |
-32.2K |
-41.52% |
$440.30 |
45.4K |
Nov 14, 2025 |
Direct |
F1, F2, F5 |
| transaction |
VRTX |
Common Stock |
Sale |
-$9.41M |
-21.3K |
-46.99% |
$441.35 |
24.1K |
Nov 14, 2025 |
Direct |
F1, F2, F6 |
| transaction |
VRTX |
Common Stock |
Sale |
-$17.7K |
-40 |
-0.17% |
$442.00 |
24K |
Nov 14, 2025 |
Direct |
F1 |
| holding |
VRTX |
Common Stock |
|
|
|
|
|
440 |
Nov 13, 2025 |
401(k) |
|
Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)
| Type |
Sym |
Class |
Transaction |
Value $ |
Shares |
Change % |
* Price $ |
Shares After |
Date |
Underlying Class |
Amount |
Exercise Price |
Ownership |
Footnotes |
| transaction |
VRTX |
Stock Option (Right to Buy) |
Options Exercise |
$0 |
-19.7K |
-58.73% |
$0.00 |
13.8K |
Nov 13, 2025 |
Common Stock |
19.7K |
$91.05 |
Direct |
F7 |
| transaction |
VRTX |
Stock Option (Right to Buy) |
Options Exercise |
$0 |
-13.8K |
-99.99% |
$0.00 |
1 |
Nov 14, 2025 |
Common Stock |
13.8K |
$91.05 |
Direct |
F7 |
| transaction |
VRTX |
Stock Option (Right to Buy) |
Options Exercise |
$0 |
-39.8K |
-38.41% |
$0.00 |
63.8K |
Nov 14, 2025 |
Common Stock |
39.8K |
$86.52 |
Direct |
F7 |
* An asterisk sign (*) next to the price indicates that the price is likely invalid.
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
Explanation of Responses: