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Signature
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By: Patrick R. O'Neil, attorney-in-fact For: Joseph Klein, III
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Stock symbol
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IONS
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Transactions as of
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Nov 25, 2025
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Transactions value $
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-$960,000
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Form type
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4
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Date filed
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11/28/2025, 05:51 PM
Reporting Owners (1)
| Name |
Relationship |
Address |
Signature |
Signature date |
CIK |
| KLEIN JOSEPH III |
Director |
2855 GAZELLE COURT, CARLSBAD |
By: Patrick R. O'Neil, attorney-in-fact For: Joseph Klein, III |
2025-11-28 |
0001206369 |
Transactions Table
| Type |
Sym |
Class |
Transaction |
Value $ |
Shares |
Change % |
* Price $ |
Shares After |
Date |
Ownership |
Footnotes |
| transaction |
IONS |
Common Stock |
Options Exercise |
$0 |
+4K |
|
$0.00 |
4K |
Nov 25, 2025 |
by Trust |
|
| transaction |
IONS |
Common Stock |
Sale |
-$320K |
-4K |
-100% |
$80.00 |
0 |
Nov 25, 2025 |
by Trust |
F1, F2 |
| transaction |
IONS |
Common Stock |
Options Exercise |
$0 |
+4K |
|
$0.00 |
4K |
Nov 25, 2025 |
by Trust |
|
| transaction |
IONS |
Common Stock |
Sale |
-$320K |
-4K |
-100% |
$80.00 |
0 |
Nov 25, 2025 |
by Trust |
F1, F2 |
| transaction |
IONS |
Common Stock |
Options Exercise |
$0 |
+4K |
|
$0.00 |
4K |
Nov 25, 2025 |
by Trust |
|
| transaction |
IONS |
Common Stock |
Sale |
-$320K |
-4K |
-100% |
$80.00 |
0 |
Nov 25, 2025 |
by Trust |
F1, F2 |
| holding |
IONS |
Common Stock |
|
|
|
|
|
16.3K |
Nov 25, 2025 |
Direct |
|
| holding |
IONS |
Common Stock |
|
|
|
|
|
100 |
Nov 25, 2025 |
by Son |
F3 |
Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)
| Type |
Sym |
Class |
Transaction |
Value $ |
Shares |
Change % |
* Price $ |
Shares After |
Date |
Underlying Class |
Amount |
Exercise Price |
Ownership |
Footnotes |
| transaction |
IONS |
Non-Qualified Stock Option (right to buy) |
Options Exercise |
$0 |
-4K |
-33.33% |
$0.00 |
8K |
Nov 25, 2025 |
Common Stock |
4K |
$60.20 |
by Trust |
|
| transaction |
IONS |
Non-Qualified Stock Option (right to buy) |
Options Exercise |
$0 |
-4K |
-50% |
$0.00 |
4K |
Nov 25, 2025 |
Common Stock |
4K |
$60.20 |
by Trust |
|
| transaction |
IONS |
Non-Qualified Stock Option (right to buy) |
Options Exercise |
$0 |
-4K |
-100% |
$0.00 |
0 |
Nov 25, 2025 |
Common Stock |
4K |
$60.20 |
by Trust |
|
* An asterisk sign (*) next to the price indicates that the price is likely invalid.
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
Explanation of Responses: