Michael R. Hayden - 15 Jul 2025 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Role
Director
Signature
By: Patrick R. O'Neil, attorney-in-fact For: Michael R. Hayden
Issuer symbol
IONS
Transactions as of
15 Jul 2025
Net transactions value
$0
Form type
4
Filing time
17 Jul 2025, 16:54:01 UTC
Previous filing
02 Jul 2025
Next filing
30 Oct 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Hayden Michael R Director 2855 GAZELLE COURT, CARLSBAD By: Patrick R. O'Neil, attorney-in-fact For: Michael R. Hayden 17 Jul 2025 0001352908

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction IONS Common Stock Options Exercise $0 +4,079 +8.1% $0.000000 54,298 15 Jul 2025 Direct F1
holding IONS Common Stock 2,000 15 Jul 2025 by Spouse F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction IONS Restricted Stock Unit Options Exercise $0 -4,079 -29% $0.000000 9,897 15 Jul 2025 Common Stock 4,079 $0.000000 Direct F3, F4
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.
F2 These securities are held by Genworks 2 Consulting, Inc. ("Genworks 2"). The Reporting Person's spouse has sole voting and investment power with respect to the shares held by Genworks 2.
F3 Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.
F4 Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.