Michael J. Yang - Dec 14, 2023 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Role: Director
Signature: By: Patrick R. O'Neil, attorney-in-fact For: Michael J. Yang
Stock symbol: IONS
Transactions as of: Dec 14, 2023
Transactions value $: $0
Form type: 4
Date filed: 12/18/2023, 04:58 PM
Previous filing: Oct 11, 2023
Next filing: Jan 17, 2024

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	IONS	Non-Qualified Stock Option (right to buy)	Award	$0	+12.4K		$0.00	12.4K	Dec 14, 2023	Common Stock	12.4K	$49.82	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Grant of 12/14/2023 to reporting person of stock options under the Ionis Pharmaceuticals, Inc. Amended & Restated 2002 Non-Employee Directors' Stock Option Plan. The option vests and becomes exercisable in three equal annual installments, the first installment vesting on 12/14/2024. The option shall be fully vested and exercisable on 12/14/2026. The stock option was exercisable as to 0 shares on 12/14/2023.

Content

Grant of 12/14/2023 to reporting person of stock options under the Ionis Pharmaceuticals, Inc. Amended & Restated 2002 Non-Employee Directors' Stock Option Plan. The option vests and becomes exercisable in three equal annual installments, the first installment vesting on 12/14/2024. The option shall be fully vested and exercisable on 12/14/2026. The stock option was exercisable as to 0 shares on 12/14/2023.