Eric Swayze - Sep 19, 2022 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Role: EVP Research
Signature: By: Patrick R. O'Neil, attorney-in-fact For: Eric Swayze
Stock symbol: IONS
Transactions as of: Sep 19, 2022
Transactions value $: $0
Form type: 4
Date filed: 9/21/2022, 08:08 PM
Previous filing: Sep 12, 2022
Next filing: Oct 18, 2022

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	IONS	Non-Qualified Stock Option (right to buy)	Award	$0	+1K		$0.00	1K	Sep 19, 2022	Common Stock	1K	$46.74	by Son	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Grant on 9/19/2022 to reporting person's son of stock options under the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan. Following this transaction, the option was exercisable as to 0 shares on 9/19/2022. 25% of the shares subject to the option will vest and become exercisable on 9/19/2023. Thereafter, the remaining shares subject to the option will vest and become exercisable in 36 equal monthly installments over the next 3 years.

Content

Grant on 9/19/2022 to reporting person's son of stock options under the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan. Following this transaction, the option was exercisable as to 0 shares on 9/19/2022. 25% of the shares subject to the option will vest and become exercisable on 9/19/2023. Thereafter, the remaining shares subject to the option will vest and become exercisable in 36 equal monthly installments over the next 3 years.