Patrick R. O'neil - Apr 12, 2022 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Role: EVP CLO & General Counsel
Signature: Patrick R. O'Neil
Stock symbol: IONS
Transactions as of: Apr 12, 2022
Transactions value $: -$272,057
Form type: 4
Date filed: 4/14/2022, 06:02 PM
Previous filing: Mar 2, 2022
Next filing: Sep 1, 2022

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	IONS	Common Stock	Sale	-$272K	-6.79K	-16.43%	$40.06	34.5K	Apr 12, 2022	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 6, 2020.
F2	The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.75 to $40.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.

Content

Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 6, 2020.

The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.75 to $40.25, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.