Eugene Schneider - 15 Oct 2021 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Role: EVP, Chf Clinical Develop Offc
Signature: By: Patrick R. O'Neil, attorney-in-fact For: Eugene Schneider
Issuer symbol: IONS
Transactions as of: 15 Oct 2021
Net transactions value: -$5,090
Form type: 4
Filing time: 19 Oct 2021, 18:29:37 UTC
Previous filing: 19 Apr 2023
Next filing: 05 Jan 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	IONS	Common Stock	Options Exercise	$0	+417	+6%	$0.000000	7,320	15 Oct 2021	Direct	F1
transaction	IONS	Common Stock	Tax liability	$5,090	-145	-2%	$35.10	7,175	15 Oct 2021	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	IONS	Restricted Stock Unit	Options Exercise	$0	-417	-1.3%	$0.000000	30,592	15 Oct 2021	Common Stock	417	$0.000000	Direct	F3, F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.
F2	Shares withheld to cover the required tax withholding obligations pursuant to the Ionis Pharmaceuticals, Inc. Amended and Restated 2011 Equity Incentive Plan.
F3	Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.
F4	Restricted Stock Units vest in four equal annual installments. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.