| Quarter | Holdings | Value $ | Bought | Sold | Net | Top Holdings | Form Type | Date Filed |
|---|---|---|---|---|---|---|---|---|
| Q3 2015 | 5 | $1.07B | +$622M | -$194M | +$428M | GBT, SAGE, BPMC, EBIO, ZFGN | 13F-HR | 11/3/2015, 01:41 PM |
| Q2 2015 | 4 | $961M | +$196M | -$345M | -$149M | SAGE, BPMC, ZFGN, EBIO | 13F-HR | 7/30/2015, 12:51 PM |
| Q1 2015 | 4 | $938M | $0 | -$607M | -$607M | SAGE, FMI, ZFGN, EBIO | 13F-HR | 4/29/2015, 04:57 PM |
| Q4 2014 | 6 | $1.22B | $0 | $0 | SAGE, AGIO, ZFGN, BLUE, FMI | 13F-HR | 1/26/2015, 04:07 PM | |
| Q3 2014 | 6 | $857M | +$478M | -$93.7M | +$384M | SAGE, AGIO, ZFGN, FMI, EBIO | 13F-HR | 10/22/2014, 03:03 PM |
| Q2 2014 | 4 | $468M | $0 | -$121M | -$121M | AGIO, FMI, BLUE, EBIO | 13F-HR | 7/30/2014, 02:31 PM |
| Q1 2014 | 4 | $564M | +$78.6M | -$20.4M | +$58.2M | AGIO, FMI, EBIO, BLUE | 13F-HR | 4/30/2014, 02:19 PM |
| Q4 2013 | 3 | $353M | $0 | $0 | FMI, AGIO, BLUE | 13F-HR | 2/14/2014, 03:44 PM |