SPHERA FUNDS MANAGEMENT LTD.

Holdings History for OnKure Therapeutics, Inc. - Class A Common Stock, par value $0.0001 per share (OKUR)

Symbol: OKUR on Nasdaq
Investment type: Equity / Class A Common Stock, par value $0.0001 per share

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025	0.04%	0%	$175,317	60,454	0		$2.90	Q4 2025
30 Sep 2025	0.04%	0%	$166,249	60,454	0		$2.75	Q3 2025
30 Jun 2025	0.04%	-0.01%	$144,485	60,454	-20,000	-25%	$2.39	Q2 2025
31 Mar 2025	0.09%	-0.01%	$345,952	80,454	-6,900		$4.30	Q1 2025
31 Dec 2024	0.14%	+0.14%	$751,244	87,354	+87,354	NEW	$8.60	Q4 2024

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.