TWO SIGMA SECURITIES, LLC

Holdings History for Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS)

Symbol: ANVS on NYSE
Investment type: Equity / Common Stock, par value $0.0001 per share

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025		-0%	$0	0	-10,511	-100%	$2.60	Q4 2025
30 Sep 2025	0%	+0%	$21,758	10,511	+10,511	NEW	$2.07	Q3 2025
31 Mar 2024		-0.01%	$0	0	-12,282	-100%	$2.60	Q1 2024
31 Dec 2023	0.01%	+0.01%	$229,673	12,282	+12,282	NEW	$18.70	Q4 2023

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.