BAKER BROS. ADVISORS LP

Holdings History for ZYMEWORKS INC - COM (ZYME)

Symbol: ZYME on Nasdaq
Investment type: Equity / COM

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2022		-0.07%	$0	0	-1,708,472	-100%		Q4 2022
30 Sep 2022	0.07%	0%	$10,507,000	1,708,472	0		$6.15	Q3 2022
30 Jun 2022	0.05%	0%	$9,055,000	1,708,472	0		$5.30	Q2 2022
31 Mar 2022	0.06%	0%	$11,190,000	1,708,472	0		$6.55	Q1 2022
31 Dec 2021	0.14%	0%	$28,002,000	1,708,472	0		$16.39	Q4 2021
30 Sep 2021	0.22%	0%	$49,614,000	1,708,472	0		$29.04	Q3 2021
30 Jun 2021	0.26%	0%	$59,267,000	1,708,472	0		$34.69	Q2 2021
31 Mar 2021	0.23%	0%	$53,954,000	1,708,472	0		$31.58	Q1 2021
31 Dec 2020	0.3%	0%	$80,742,000	1,708,472	0		$47.26	Q4 2020
30 Sep 2020	0.32%	0%	$79,581,000	1,708,472	0		$46.58	Q3 2020
30 Jun 2020	0.27%	0%	$61,625,000	1,708,472	0		$36.07	Q2 2020
31 Mar 2020	0.37%	0%	$60,600,000	1,708,472	0		$35.47	Q1 2020
31 Dec 2019	0.41%	0%	$77,667,000	1,708,472	0		$45.46	Q4 2019
30 Sep 2019	0.29%	0%	$42,370,000	1,708,472	0		$24.80	Q3 2019
30 Jun 2019	0.26%	0%	$37,586,000	1,708,472	0		$22.00	Q2 2019
31 Mar 2019	0.18%	0%	$27,643,000	1,708,472	0		$16.18	Q1 2019
31 Dec 2018	0.21%	+0.05%	$25,080,000	1,708,472	+397,387	+30%	$14.68	Q4 2018
30 Sep 2018	0.14%	0%	$20,584,000	1,311,085	0		$15.70	Q3 2018
30 Jun 2018	0.15%	+0.15%	$19,378,000	1,311,085	+1,311,085	NEW	$14.78	Q2 2018

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.