BAKER BROS. ADVISORS LP

Holdings History for ACCELERON PHARMA INC - COMMON STOCK (XLRN)

Symbol: XLRN
Investment type: Equity / COMMON STOCK

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2021		-0.02%	$0	0	-22,430	-100%	$179.00	Q4 2021
30 Sep 2021	0.02%	0%	$3,860,000	22,430	0		$172.09	Q3 2021
30 Jun 2021	0.01%	0%	$2,815,000	22,430	0		$125.50	Q2 2021
31 Mar 2021	0.01%	0%	$3,042,000	22,430	0		$135.62	Q1 2021
31 Dec 2020	0.01%	-0%	$2,870,000	22,430	-3,210	-13%	$127.95	Q4 2020
30 Sep 2020	0.01%	-0%	$2,885,000	25,640	-1,360	-5%	$112.52	Q3 2020
30 Jun 2020	0.01%	0%	$2,572,000	27,000	0		$95.26	Q2 2020
31 Mar 2020	0.01%	+0.01%	$2,426,000	27,000	+27,000	NEW	$89.85	Q1 2020
31 Dec 2019		-0.02%	$0	0	-83,900	-100%	$179.00	Q4 2019
30 Sep 2019	0.02%	0%	$3,315,000	83,900	0		$39.51	Q3 2019
30 Jun 2019	0.02%	0%	$3,447,000	83,900	0		$41.08	Q2 2019
31 Mar 2019	0.03%	0%	$3,907,000	83,900	0		$46.57	Q1 2019
31 Dec 2018	0.03%	0%	$3,654,000	83,900	0		$43.55	Q4 2018
30 Sep 2018	0.03%	-0.03%	$4,802,000	83,900	-80,000	-49%	$57.23	Q3 2018
30 Jun 2018	0.06%	0%	$7,952,000	163,900	0		$48.52	Q2 2018
31 Mar 2018	0.05%	0%	$6,408,000	163,900	0		$39.10	Q1 2018
31 Dec 2017	0.06%	0%	$6,956,000	163,900	0		$42.44	Q4 2017
30 Sep 2017	0.05%	+0.04%	$6,117,000	163,900	+135,135	+470%	$37.32	Q3 2017
30 Jun 2017	0.01%	0%	$874,000	28,765	0		$30.38	Q2 2017
31 Mar 2017	0.01%	0%	$761,000	28,765	0		$26.46	Q1 2017
31 Dec 2016	0.01%	0%	$734,000	28,765	0		$25.52	Q4 2016
30 Sep 2016	0.01%	0%	$1,041,000	28,765	0		$36.19	Q3 2016
30 Jun 2016	0.01%	0%	$977,000	28,765	0		$33.96	Q2 2016
31 Mar 2016	0.01%	0%	$759,000	28,765	0		$26.39	Q1 2016
31 Dec 2015	0.01%	0%	$1,403,000	28,765	0		$48.77	Q4 2015
30 Sep 2015	0.01%	0%	$716,000	28,765	0		$24.89	Q3 2015
30 Jun 2015	0.01%	0%	$910,000	28,765	0		$31.64	Q2 2015
31 Mar 2015	0.01%	0%	$1,095,000	28,765	0		$38.07	Q1 2015
31 Dec 2014	0.01%	0%	$1,121,000	28,765	0		$38.97	Q4 2014
30 Sep 2014	0.01%	0%	$870,000	28,765	0		$30.25	Q3 2014
30 Jun 2014	0.01%	0%	$977,000	28,765	0		$33.96	Q2 2014
31 Mar 2014	0.01%	-0%	$992,000	28,765	-1,235	-4.1%	$34.49	Q1 2014
31 Dec 2013	0.02%	0%	$1,188,000	30,000	0		$39.60	Q4 2013

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.