TWO SIGMA INVESTMENTS, LP

Holdings History for Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD)

Symbol: IRD on Nasdaq
Investment type: Equity / Common Stock, $0.0001 par value per share

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025	0%	+0%	$304,137	151,312	+42,974	+40%	$2.01	Q4 2025
30 Sep 2025	0%	+0%	$178,758	108,338	+68,148	+170%	$1.65	Q3 2025
30 Jun 2025	0%	+0%	$37,863	40,190	+40,190	NEW	$0.94	Q2 2025
30 Sep 2023		-0%	$0	0	-19,086	-100%	$3.64	Q3 2023
30 Jun 2023	0%	+0%	$82,833	19,086	+19,086	NEW	$4.34	Q2 2023
30 Jun 2022		-0%	$0	0	-51,700	-100%	$3.64	Q2 2022
31 Mar 2022	0%	-0%	$168,000	51,700	-68,200	-57%	$3.25	Q1 2022
31 Dec 2021	0%	+0%	$447,000	119,900	+83,017	+225%	$3.73	Q4 2021
30 Sep 2021	0%	+0%	$190,000	36,883	+36,883	NEW	$5.15	Q3 2021

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.