ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

Holdings History for Spero Therapeutics, Inc. - Common Stock, par value $0.001 per share (SPRO)

Symbol: SPRO on Nasdaq
Investment type: Equity / Common Stock, par value $0.001 per share

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025		-0%	$0	0	-150,516	-100%	$2.37	Q4 2025
30 Sep 2025	0%	+0%	$282,970	150,516	+150,516	NEW	$1.88	Q3 2025
31 Dec 2020		-0%	$0	0	-34,225	-100%	$2.37	Q4 2020
30 Sep 2020	0%	+0%	$382,000	34,225	+6,483	+23%	$11.16	Q3 2020
30 Jun 2020	0%	+0%	$375,000	27,742	+27,742	NEW	$13.52	Q2 2020

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.