Type / Class
Equity / Common Stock, par value $0.001 per share
Shares outstanding
55,705,828
Total 13F shares
21,119,398
Share change
+658,135
Total reported value
$49,213,763
Price per share
$2.33
Number of holders
56
Value change
+$1,640,743
Number of buys
29
Number of sells
18

Institutional Holders of Spero Therapeutics, Inc. - Common Stock, par value $0.001 per share (SPRO) as of Q4 2025

As of 31 Dec 2025, Spero Therapeutics, Inc. - Common Stock, par value $0.001 per share (SPRO) was held by 56 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 21,119,398 shares. The largest 10 holders included GSK plc, Pfizer Inc, VANGUARD GROUP INC, RENAISSANCE TECHNOLOGIES LLC, Alphabet Inc., Anson Funds Management LP, GEODE CAPITAL MANAGEMENT, LLC, BlackRock, Inc., CITADEL ADVISORS LLC, and TWO SIGMA INVESTMENTS, LP. This page lists 56 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.