ORBIMED ADVISORS LLC

Holdings History for LOXO ONCOLOGY INC - COM (LOXO)

Symbol: LOXO
Investment type: Equity / COM

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2018		-0.68%	$0	0	-330,000	-100%		Q4 2018
30 Sep 2018	0.68%	-0.43%	$56,374,000	330,000	-208,000	-39%	$170.83	Q3 2018
30 Jun 2018	1.1%	-0.84%	$93,332,000	538,000	-403,000	-43%	$173.48	Q2 2018
31 Mar 2018	1.4%	0%	$108,563,000	941,000	0		$115.37	Q1 2018
31 Dec 2017		0%	$79,213,000	94,100,036	0		$0.84 ^*	Q4 2017
30 Sep 2017	1.5%	0%	$159,183,000	1,728,000	0		$92.12	Q3 2017
30 Jun 2017	1.5%	0%	$138,568,000	1,728,000	0		$80.19	Q2 2017
31 Mar 2017	0.83%	0%	$72,714,000	1,728,000	0		$42.08	Q1 2017
31 Dec 2016	0.71%	0%	$55,495,000	1,728,000	0		$32.12	Q4 2016
30 Sep 2016	0.52%	-0.13%	$45,239,000	1,728,000	-447,857	-21%	$26.18	Q3 2016
30 Jun 2016	0.53%	0%	$50,436,000	2,175,857	0		$23.18	Q2 2016
31 Mar 2016	0.63%	0%	$59,488,000	2,175,857	0		$27.34	Q1 2016
31 Dec 2015	0.56%	0%	$61,903,000	2,175,857	0		$28.45	Q4 2015
30 Sep 2015	0.38%	0%	$38,034,000	2,175,857	0		$17.48	Q3 2015
30 Jun 2015	0.33%	0%	$39,231,000	2,175,857	0		$18.03	Q2 2015
31 Mar 2015	0.24%	0%	$27,089,000	2,175,857	0		$12.45	Q1 2015
31 Dec 2014	0.25%	0%	$25,566,000	2,175,857	0		$11.75	Q4 2014
30 Sep 2014	0.32%	+0.32%	$28,569,000	2,175,857	+2,175,857	NEW	$13.13	Q3 2014

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.