Artal Group S.A.

Holdings History for AGIOS PHARMACEUTICALS, INC. - Common stock, par value $0.0001 per share (AGIO)

Symbol: AGIO on Nasdaq
Investment type: Equity / Common stock, par value $0.0001 per share

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Option	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
30 Sep 2020			-0.69%	$0	0	-376,000	-100%	$27.56	Q3 2020
30 Jun 2020		0.69%	-0.04%	$20,108,000	376,000	-24,000	-6%	$53.48	Q2 2020
31 Mar 2020		0.68%	-0.34%	$14,192,000	400,000	-200,000	-33%	$35.48	Q1 2020
31 Dec 2019		1.2%	+0.4%	$28,650,000	600,000	+200,000	+50%	$47.75	Q4 2019
30 Sep 2019		0.63%	-0.16%	$12,960,000	400,000	-100,000	-20%	$32.40	Q3 2019
30 Sep 2019	call		-1.7%	$0	0	-100,000	-100%	$27.56	Q3 2019
30 Jun 2019		1.1%	+0.23%	$24,940,000	500,000	+100,000	+25%	$49.88	Q2 2019
30 Jun 2019	call	1.7%	-1.7%	$4,988,000	100,000	-100,000	-50%	$49.88	Q2 2019
31 Mar 2019		1.3%	0%	$26,976,000	400,000	0		$67.44	Q1 2019
31 Mar 2019	call	3.8%	0%	$13,488,000	200,000	0		$67.44	Q1 2019
31 Dec 2018		0.92%	+0.23%	$18,444,000	400,000	+100,000	+33%	$46.11	Q4 2018
31 Dec 2018	call	1.3%	+1.3%	$9,222,000	200,000	+200,000	NEW	$46.11	Q4 2018
30 Sep 2018		0.8%	-0.13%	$23,136,000	300,000	-50,000	-14%	$77.12	Q3 2018
30 Sep 2018	call		-0.48%	$0	0	-50,000	-100%	$27.56	Q3 2018
30 Jun 2018		0.77%	-0.33%	$29,481,000	350,000	-150,000	-30%	$84.23	Q2 2018
30 Jun 2018	call	0.48%	0%	$4,212,000	50,000	0		$84.24	Q2 2018
31 Mar 2018		0.6%	0%	$40,890,000	500,000	0		$81.78	Q1 2018
31 Mar 2018	call	0.34%	-0.34%	$4,089,000	50,000	-50,000	-50%	$81.78	Q1 2018
31 Dec 2017		0.53%	+0.05%	$28,585,000	500,000	+50,000	+11%	$57.17	Q4 2017
31 Dec 2017	call	0.46%	+0.46%	$5,717,000	100,000	+100,000	NEW	$57.17	Q4 2017
30 Sep 2017		0.6%	-0.33%	$30,038,000	450,000	-250,000	-36%	$66.75	Q3 2017
30 Sep 2017	call		-0.43%	$0	0	-100,000	-100%	$27.56	Q3 2017
30 Jun 2017		0.8%	-0.06%	$36,015,000	700,000	-50,000	-6.7%	$51.45	Q2 2017
30 Jun 2017	call	0.43%	0%	$5,145,000	100,000	0		$51.45	Q2 2017
31 Mar 2017		1.1%	0%	$43,800,000	750,000	0		$58.40	Q1 2017
31 Mar 2017	call	0.93%	-4.7%	$5,840,000	100,000	-500,000	-83%	$58.40	Q1 2017
31 Dec 2016		0.85%	+0.4%	$31,298,000	750,000	+350,000	+88%	$41.73	Q4 2016
31 Dec 2016	call	3.1%	+0.52%	$25,038,000	600,000	+100,000	+20%	$41.73	Q4 2016
30 Sep 2016		0.53%	+0.03%	$21,128,000	400,000	+25,000	+6.7%	$52.82	Q3 2016
30 Sep 2016	call	2.5%	+2.5%	$26,410,000	500,000	+500,000	NEW	$52.82	Q3 2016
30 Jun 2016		0.36%	+0.04%	$15,711,000	375,000	+40,000	+12%	$41.90	Q2 2016
30 Jun 2016	call		-1.4%	$0	0	-200,000	-100%	$27.56	Q2 2016
31 Mar 2016		0.3%	+0.05%	$13,601,000	335,000	+60,000	+22%	$40.60	Q1 2016
31 Mar 2016	call	1.4%	+0.72%	$8,120,000	200,000	+100,000	+100%	$40.60	Q1 2016
31 Dec 2015		0.43%	+0.08%	$17,853,000	275,000	+50,000	+22%	$64.92	Q4 2015
31 Dec 2015	call	0.55%	+0.55%	$6,492,000	100,000	+100,000	NEW	$64.92	Q4 2015
30 Sep 2015		0.48%	+0.14%	$15,883,000	225,000	+65,000	+41%	$70.59	Q3 2015
30 Jun 2015		1.4%	+0.17%	$17,782,000	160,000	+20,000	+14%	$111.14	Q2 2015
31 Mar 2015		0.99%	+0.35%	$13,202,000	140,000	+50,000	+56%	$94.30	Q1 2015
31 Dec 2014		0.61%	-0.67%	$10,084,000	90,000	-100,000	-53%	$112.04	Q4 2014
30 Sep 2014		0.72%	+0.06%	$11,657,000	190,000	+15,000	+8.6%	$61.35	Q3 2014
30 Jun 2014		0.59%	+0.25%	$8,019,000	175,000	+75,000	+75%	$45.82	Q2 2014
31 Mar 2014		0.27%	-0.03%	$3,915,000	100,000	-10,000	-9.1%	$39.15	Q1 2014
31 Dec 2013		0.15%	0%	$2,635,000	110,000	0		$23.95	Q4 2013

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.