TIAA CREF INVESTMENT MANAGEMENT LLC

Holdings History for AGIOS PHARMACEUTICALS, INC. - Common stock, par value $0.0001 per share (AGIO)

Symbol: AGIO on Nasdaq
Investment type: Equity / Common stock, par value $0.0001 per share

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Mar 2019	0.01%	+0%	$10,657,000	158,029	+9,635	+6.5%	$67.44	Q1 2019
31 Dec 2018	0.01%	-0%	$6,842,000	148,394	-606	-0.41%	$46.11	Q4 2018
30 Sep 2018	0.01%	+0%	$11,491,000	149,000	+2,202	+1.5%	$77.12	Q3 2018
30 Jun 2018	0.01%	+0%	$12,365,000	146,798	+24,785	+20%	$84.23	Q2 2018
31 Mar 2018	0.01%	+0%	$9,978,000	122,013	+13,644	+13%	$81.78	Q1 2018
31 Dec 2017	0%	-0%	$6,195,000	108,369	-4,444	-3.9%	$57.17	Q4 2017
30 Sep 2017	0.01%	-0%	$7,530,000	112,813	-4,452	-3.8%	$66.75	Q3 2017
30 Jun 2017	0%	+0%	$6,033,000	117,265	+28,030	+31%	$51.45	Q2 2017
31 Mar 2017	0%	-0%	$5,211,000	89,235	-4,462	-4.8%	$58.40	Q1 2017
31 Dec 2016	0%	+0%	$3,910,000	93,697	+9,285	+11%	$41.73	Q4 2016
30 Sep 2016	0%	+0%	$4,459,000	84,412	+3,636	+4.5%	$52.82	Q3 2016
30 Jun 2016	0%	+0%	$3,384,000	80,776	+5,852	+7.8%	$41.89	Q2 2016
31 Mar 2016	0%	-0%	$3,042,000	74,924	-1,856	-2.4%	$40.60	Q1 2016
31 Dec 2015	0%	-0%	$4,985,000	76,780	-100	-0.13%	$64.93	Q4 2015
30 Sep 2015	0%	-0%	$5,427,000	76,880	-30,426	-28%	$70.59	Q3 2015
30 Jun 2015	0.01%	+0%	$11,926,000	107,306	+58,305	+119%	$111.14	Q2 2015
31 Mar 2015	0%	+0%	$4,621,000	49,001	+850	+1.8%	$94.30	Q1 2015
31 Dec 2014	0%	-0%	$5,395,000	48,151	-1,584	-3.2%	$112.04	Q4 2014
30 Sep 2014	0%	-0%	$3,051,000	49,735	-1,072	-2.1%	$61.35	Q3 2014
30 Jun 2014	0%	+0%	$2,328,000	50,807	+22,775	+81%	$45.82	Q2 2014
31 Mar 2014	0%	0%	$1,097,000	28,032	0		$39.13	Q1 2014
31 Dec 2013	0%	0%	$671,000	28,032	0		$23.94	Q4 2013

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.