How many institutions held PRTA - PROTHENA CORP PUBLIC LTD CO - Ordinary Shares, $0.01 par value in Q4 2021?

178 institutional investors reported PRTA - PROTHENA CORP PUBLIC LTD CO - Ordinary Shares, $0.01 par value for Q4 2021. Use the holders table for investor-level position and value details.

PROTHENA CORP PUBLIC LTD CO - Ordinary Shares, $0.01 par value (PRTA)

Q: What does CUSIP G72800108 represent in this 13F holders report?

CUSIP G72800108 is the security identifier for PRTA - PROTHENA CORP PUBLIC LTD CO - Ordinary Shares, $0.01 par value used to aggregate holder disclosures.

CUSIP: G72800108

Q4 2021 13F Holders as of 31 Dec 2021

Security type / class: Equity / Ordinary Shares, $0.01 par value
Total 13F shares: 42,838,679
Total 13F value: $2,116,102,912
Share change: +1,753,977
Put/Call ratio: 54%
SEC-reported price per share: $49.40
Number of holders: 178
Value change: +$71,220,544
Number of buys: 98
Number of sells: 69
Shares outstanding: 51,459,275

Security key

G72800108

Report period

Q4 2021

Institutions

178

Top holders

PRTA full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2026 PROTHENA CORP PUBLIC LTD CO SEC filings PROTHENA CORP PUBLIC LTD CO company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP G72800108

Newer quarter: Q3 2026

Recent filing periods:

Q3 2026

Ownership snapshot

Top reported holders of PRTA - PROTHENA CORP PUBLIC LTD CO - Ordinary Shares, $0.01 par value (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

EcoR1 Capital, LLC

Disclosed value leader

EcoR1 Capital, LLC

Comparable rows

0/15

Latest evidence

30 Sep 2021

13F Highest disclosed value: $803,779,000 15 rows are not safely comparable across share classes. Showing 1-6 of 15 holder rows.

Quick read

EcoR1 Capital, LLC has the largest disclosed position value at $803.78M.

0 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens EcoR1 Capital, LLC's linked filing trail.

Disclosed position value Top 5

EcoR1 Capital, LLC $803.78M

PRICE T ROWE ASSOCIATES INC /MD/ $431.84M

BlackRock Finance, Inc. $268.52M

FMR LLC $188.72M

Palo Alto Investors LP $120.04M

Value bars compare disclosed positions; verify each figure against the linked filing evidence.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
EcoR1 Capital, LLC	13F Company 13F	— denominator unverified	$803,779,000 11,284,280 shares	—	30 Sep 2021
PRICE T ROWE ASSOCIATES INC /MD/	13F Company 13F	— denominator unverified	$431,841,000 6,062,629 shares	—	30 Sep 2021
BlackRock Finance, Inc.	13F Company 13F	— denominator unverified	$268,517,000 3,769,704 shares	—	30 Sep 2021
FMR LLC	13F Company 13F	— denominator unverified	$188,719,000 2,649,427 shares	—	30 Sep 2021
Palo Alto Investors LP	13F Company 13F	— denominator unverified	$120,043,000 1,685,282 shares	—	30 Sep 2021
DIMENSIONAL FUND ADVISORS LP	13F Company 13F	— denominator unverified	$112,518,000 1,579,648 shares	—	30 Sep 2021

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2021

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

178

42,838,679

Rows available

178

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

178

Q4 2021 holders

178

Holder diff

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 value	Q4 2021 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend