Latest Period
Q4 2025
Security Snapshot
CRESCENT BIOPHARMA, INC. - Ordinary Shares, $0.001 par value per share (CBIO) Institutional Ownership
CUSIP: G2545C104
13F Institutional Holders and Ownership History from Q2 2025 to Q1 2026
Institutions Reporting
54
Shares (Excl. Options)
23,741,798
Price
$11.86
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- Type / Class
- Equity / Ordinary Shares, $0.001 par value per share
- Symbol
- CBIO on Nasdaq
- Shares outstanding
- 28,063,832
- Price per share
- $19.40
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 23,741,798
- Total reported value
- $281,443,423
- % of total 13F portfolios
- 0%
- Share change
- +12,046,496
- Value change
- +$142,716,069
- Number of holders
- 54
- Price from insider filings
- $19.40
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- CBIO - CRESCENT BIOPHARMA, INC. - Ordinary Shares, $0.001 par value per share is tracked under CUSIP G2545C104.
- 54 institutions reported positions in Q4 2025.
- 8 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 54 to 9 between Q4 2025 and Q1 2026.
- Reported value moved from $281,443,423 to $20,216,902.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 54 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP G2545C104?
CUSIP G2545C104 identifies CBIO - CRESCENT BIOPHARMA, INC. - Ordinary Shares, $0.001 par value per share in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP G2545C104:
Significant Owners of CRESCENT BIOPHARMA, INC. - Ordinary Shares, $0.001 par value per share (CBIO) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Fairmount Funds Management LLC | 19% | -7.3% | $73,252,396 | +$32,700,021 | 5,643,482 | +81% | Fairmount Funds Management LLC | 04 Dec 2025 |
| FMR LLC | 15% | $49,932,849 | 4,133,514 | FMR LLC | 31 Dec 2025 | |||
| Venrock Healthcare Capital Partners III, L.P. | 9.5% | $29,460,007 | 2,666,064 | Venrock Healthcare Capital Partners III, L.P. | 31 Dec 2025 | |||
| ForGrowth III PA B.V. | 6.1% | $21,778,519 | 1,677,852 | ForGrowth III PA B.V. | 08 Dec 2025 | |||
| Vestal Point Capital, LP | 5.4% | $16,575,000 | 1,500,000 | Vestal Point Capital, LP | 31 Dec 2025 | |||
| BIOTECHNOLOGY VALUE FUND L P | 10% | $18,736,150 | 1,387,863 | BVF PARTNERS L P/IL | 30 Jun 2025 | |||
| TANG CAPITAL MANAGEMENT LLC | 5% | $8,785,000 | 700,000 | TANG CAPITAL MANAGEMENT, LLC | 02 Oct 2025 | |||
| Logos Global Management LP | 4.1% | $7,762,500 | 575,000 | Logos Global Management LP | 30 Jun 2025 |
As of 31 Dec 2025, 54 institutional investors reported holding 23,741,798 shares of CRESCENT BIOPHARMA, INC. - Ordinary Shares, $0.001 par value per share (CBIO). This represents 85% of the company’s total 28,063,832 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of CRESCENT BIOPHARMA, INC. - Ordinary Shares, $0.001 par value per share (CBIO) together control 81% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 15% | 4,133,514 | +192% | 0% | $49,023,476 |
| BVF INC/IL | 9.8% | 2,748,763 | +98% | 1.1% | $32,600,329 |
| Fairmount Funds Management LLC | 9.8% | 2,747,866 | +98% | 2.5% | $32,589,691 |
| VR ADVISER, LLC | 7.6% | 2,133,576 | +54% | 1.2% | $25,304,211 |
| FCPM III SERVICES B.V. | 6% | 1,677,852 | 2.6% | $19,899,325 | |
| Vestal Point Capital, LP | 5.3% | 1,500,000 | 0.65% | $17,790,000 | |
| Opaleye Management Inc. | 4.2% | 1,178,300 | 1.9% | $13,974,638 | |
| TANG CAPITAL MANAGEMENT LLC | 3.1% | 872,398 | +28% | 0.51% | $10,346,640 |
| ADAR1 Capital Management, LLC | 2.2% | 606,000 | 0.54% | $7,187,160 | |
| Logos Global Management LP | 2.1% | 600,000 | 0% | 0.47% | $7,116,000 |
| VANGUARD GROUP INC | 2% | 557,506 | -15% | 0% | $6,612,021 |
| Boxer Capital Management, LLC | 1.6% | 453,686 | 0% | 1.2% | $5,380,716 |
| Deep Track Capital, LP | 1.6% | 453,686 | 0% | 0.12% | $5,380,716 |
| PERCEPTIVE ADVISORS LLC | 1.6% | 453,686 | 0% | 0.1% | $5,380,716 |
| RTW INVESTMENTS, LP | 1.3% | 372,856 | 0.04% | $4,422,072 | |
| NEXTBio Capital Management LP | 1.3% | 372,856 | 0% | 2.6% | $4,422,072 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.2% | 338,125 | -12% | 0% | $4,011,000 |
| Driehaus Capital Management LLC | 1.1% | 302,457 | 0% | 0.02% | $3,587,140 |
| Point72 Asset Management, L.P. | 1.1% | 300,000 | 0.01% | $3,558,000 | |
| Alyeska Investment Group, L.P. | 0.94% | 264,000 | 0.01% | $3,108,992 | |
| HEIGHTS CAPITAL MANAGEMENT, INC | 0.94% | 264,000 | 1.2% | $3,131,040 | |
| WELLINGTON MANAGEMENT GROUP LLP | 0.51% | 143,412 | +710% | 0% | $1,626,774 |
| TWO SIGMA INVESTMENTS, LP | 0.45% | 125,224 | +342% | 0% | $1,485,157 |
| Balyasny Asset Management L.P. | 0.4% | 111,715 | 0% | $1,324,940 | |
| BlackRock, Inc. | 0.39% | 109,230 | +0.11% | 0% | $1,295,468 |
Institutional Holders of CRESCENT BIOPHARMA, INC. - Ordinary Shares, $0.001 par value per share (CBIO) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 1,100,539 | $20,216,902 | +$3,629,580 | $18.37 | 9 |
| 2025 Q4 | 23,741,798 | $281,443,423 | +$142,716,069 | $11.86 | 54 |
| 2025 Q3 | 11,318,865 | $134,581,435 | +$2,898,876 | $11.89 | 40 |
| 2025 Q2 | 10,751,740 | $173,532,467 | +$173,532,402 | $16.14 | 29 |