Security Snapshot

Xilio Therapeutics, Inc. - Common Stock, par value $0.0001 per share (XLO) Institutional Ownership

CUSIP: 98422T100

13F Institutional Holders and Ownership History from Q4 2021 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

1

Shares (Excl. Options)

650,389

Price

$8.41

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
-37,821,734
Value change
-$89,907,489
Number of holders
1
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
6,426,426
SEC-reported price per share
$8.41
Insider filing price
$8.41
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • XLO - Xilio Therapeutics, Inc. - Common Stock, par value $0.0001 per share is tracked under CUSIP 98422T100.
  • 1 institution reported positions in Q1 2026.
  • 8 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 37 to 1 between Q4 2025 and Q1 2026.
  • SEC-reported value moved from $25,433,377 to $5,469,771.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 1 institution filings for Q1 2026.

Open SEC evidence

Security key

98422T100

Latest holder period

Q1 2026

13F holders

1

13D/G owners

8

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
8
Security
XLO
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
GILEAD SCIENCES, INC. 20% 0% $9,581,667 +$2,576,464 14,517,678 +37% GILEAD SCIENCES, INC. 31 Dec 2025
STEMPOINT CAPITAL LP 8.4% +17% $3,979,818 +$1,339,818 6,030,028 +51% StemPoint Capital LP 31 Dec 2025
Coastlands Capital LP 10% $3,742,248 5,346,069 Coastlands Capital LP 04 Dec 2025
Frazier Life Sciences Public Fund, L.P. 6.7% -32% $3,086,472 -$2,286,600 4,676,472 -43% Frazier Life Sciences Public Fund, L.P. 31 Dec 2025
AbbVie Inc. 9% $3,304,348 4,347,826 AbbVie Inc. 11 Feb 2025
Sirenia Capital Management LP 9.9% $9,611,469 1,142,862 Sirenia Capital Management LP 31 Mar 2026
Bain Capital Life Sciences Fund II, L.P. 10% +17% $5,584,417 -$47,060,014 664,021 -89% BCLS II Equity Opportunities, LP 31 Mar 2026
ORBIMED ADVISORS LLC 10% $5,399,220 642,000 ORBIMED ADVISORS LLC 31 Mar 2026

As of 31 Mar 2026, 1 institutional investors reported holding 650,389 shares of Xilio Therapeutics, Inc. - Common Stock, par value $0.0001 per share (XLO). This represents 10% of the company’s total 6,426,426 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
10%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
GILEAD SCIENCES, INC. 10% 650,389 -93% 0.26% $5,469,771
JANE STREET GROUP, LLC 0% 0 -100% $0
Pinnacle Financial Group, LLC / IL 0% 0 -100% $0
Private Wealth Management Group, LLC 0% 0 -100% $0
Key Financial Inc 0% 0 -100% $0
BlackRock, Inc. 0% 0 -100% $0
INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV 0% 0 -100% $0
Merck & Co., Inc. 0% 0 -100% $0
Mariner, LLC 0% 0 -100% $0
HRT FINANCIAL LP 0% 0 -100% $0
UBS Group AG 0% 0 -100% $0
Dunhill Financial, LLC 0% 0 -100% $0
LPL Financial LLC 0% 0 -100% $0
RAYMOND JAMES FINANCIAL INC 0% 0 -100% $0
NORTHERN TRUST CORP 0% 0 -100% $0
Sio Capital Management, LLC 0% 0 -100% $0
Stonepine Capital Management, LLC 0% 0 -100% $0
RENAISSANCE TECHNOLOGIES LLC 0% 0 -100% $0
AJU IB Investment Co., Ltd. 0% 0 -100% $0
GSA CAPITAL PARTNERS LLP 0% 0 -100% $0
Empery Asset Management, LP 0% 0 -100% $0
Velan Capital Investment Management LP 0% 0 -100% $0
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0% 0 -100% $0
FMR LLC 0% 0 -100% $0
STATE STREET CORP 0% 0 -100% $0

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
18
Latest
Q1 2026
Rows shown
1-18 of 18
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 650,389 $5,469,771 -$89,907,489 $8.41 1
2025 Q4 39,727,815 $25,433,377 +$11,324,174 $0.64 37
2025 Q3 22,051,916 $18,613,906 -$1,227,318 $0.84 36
2025 Q2 23,795,263 $16,179,092 +$854,217 $0.68 35
2025 Q1 22,528,206 $16,318,555 -$3,181,066 $0.72 35
2024 Q4 25,814,355 $24,660,128 -$144,644 $0.96 34
2024 Q3 15,911,945 $12,534,583 +$1,128,156 $0.79 32
2024 Q2 14,508,823 $13,746,216 +$1,785,264 $0.95 31
2024 Q1 12,460,895 $13,460,257 -$2,676,053 $1.08 30
2023 Q4 16,426,281 $9,034,716 -$1,543,598 $0.55 33
2023 Q3 15,860,160 $33,465,952 -$314,935 $2.11 30
2023 Q2 16,002,286 $41,925,598 -$192,245 $2.62 32
2023 Q1 16,072,057 $50,979,505 +$461,644 $3.17 32
2022 Q4 15,926,513 $42,841,966 -$709,927 $2.69 28
2022 Q3 16,606,568 $48,328,000 -$3,750,524 $2.91 28
2022 Q2 17,880,380 $52,211,910 -$3,647,986 $2.92 29
2022 Q1 18,775,939 $132,746,000 -$2,569,332 $7.07 41
2021 Q4 18,324,586 $269,421,063 +$225,248,000 $16.00 41
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