| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 6.7% | $87,815,414 | 11,186,677 | The Vanguard Group | 31 Dec 2025 |
As of 30 Sep 2025, 229 institutional investors reported holding 96,902,264 shares of Xeris Biopharma Holdings, Inc. - Common Stock (XERS). This represents 58% of the company’s total 165,974,436 outstanding shares.
The largest institutional shareholders of Xeris Biopharma Holdings, Inc. - Common Stock (XERS) together control 43% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 7.2% | 11,927,699 | +3.4% | 0% | $97,091,470 |
| VANGUARD GROUP INC | 5.9% | 9,827,917 | +0.11% | 0% | $79,999,244 |
| D. E. Shaw & Co., Inc. | 3.5% | 5,839,886 | +52% | 0.04% | $47,536,672 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.5% | 4,140,174 | +13% | 0% | $33,707,992 |
| STATE STREET CORP | 2.3% | 3,738,329 | -1.2% | 0% | $30,429,998 |
| Qube Research & Technologies Ltd | 2% | 3,274,834 | +6% | 0.04% | $26,657,149 |
| MORGAN STANLEY | 1.9% | 3,219,701 | -12% | 0% | $26,208,367 |
| Nuveen, LLC | 1.7% | 2,827,874 | +8.7% | 0.01% | $23,018,895 |
| Driehaus Capital Management LLC | 1.6% | 2,619,129 | +26% | 0.15% | $21,319,710 |
| Rosalind Advisors, Inc. | 1.1% | 1,795,766 | -17% | 5.3% | $14,617,535 |
| GOLDMAN SACHS GROUP INC | 1.1% | 1,795,455 | -21% | 0% | $14,615,004 |
| Parkman Healthcare Partners LLC | 1.1% | 1,791,674 | -15% | 1.6% | $14,584,226 |
| UBS Group AG | 1.1% | 1,782,734 | +682% | 0% | $14,511,455 |
| Connor, Clark & Lunn Investment Management Ltd. | 1% | 1,698,757 | +38% | 0.04% | $13,827,882 |
| RENAISSANCE TECHNOLOGIES LLC | 0.98% | 1,622,840 | -21% | 0.02% | $13,209,919 |
| TWO SIGMA INVESTMENTS, LP | 0.97% | 1,614,579 | +33% | 0.02% | $13,142,673 |
| BANK OF AMERICA CORP /DE/ | 0.96% | 1,594,866 | -4.1% | 0% | $12,982,208 |
| DEUTSCHE BANK AG\ | 0.94% | 1,567,645 | +113% | 0% | $12,760,630 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.87% | 1,446,619 | +155% | 0% | $11,775,479 |
| PRUDENTIAL FINANCIAL INC | 0.86% | 1,434,204 | -7.9% | 0.01% | $11,674,421 |
| NORTHERN TRUST CORP | 0.82% | 1,363,129 | +5.4% | 0% | $11,095,869 |
| Legal & General Group Plc | 0.82% | 1,357,427 | -25% | 0% | $11,049,455 |
| KENNEDY CAPITAL MANAGEMENT LLC | 0.73% | 1,211,583 | +48% | 0.22% | $9,862,286 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0.62% | 1,034,553 | +4% | 0.03% | $8,421,261 |
| Knott David M Jr | 0.61% | 1,015,000 | -4.2% | 3.5% | $8,262,100 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 13,754,651 | $107,945,928 | +$4,075,602 | $7.85 | 60 |
| 2025 Q3 | 96,902,264 | $788,823,196 | +$58,408,316 | $8.14 | 229 |
| 2025 Q2 | 90,495,534 | $422,617,978 | +$16,622,096 | $4.67 | 200 |
| 2025 Q1 | 86,799,982 | $476,523,606 | +$123,713,876 | $5.49 | 199 |
| 2024 Q4 | 65,548,446 | $222,208,577 | +$5,693,687 | $3.39 | 161 |
| 2024 Q3 | 63,918,467 | $182,169,401 | +$11,712,690 | $2.85 | 143 |
| 2024 Q2 | 60,623,914 | $136,403,872 | +$57,516 | $2.25 | 132 |
| 2024 Q1 | 60,495,199 | $133,691,334 | +$1,259,202 | $2.21 | 140 |
| 2023 Q4 | 59,921,867 | $140,817,138 | +$3,980,290 | $2.35 | 118 |
| 2023 Q3 | 55,319,172 | $102,889,496 | -$2,383,422 | $1.86 | 109 |
| 2023 Q2 | 55,920,487 | $146,506,955 | +$17,809,976 | $2.62 | 101 |
| 2023 Q1 | 49,463,144 | $80,622,599 | -$5,927,964 | $1.63 | 89 |
| 2022 Q4 | 53,916,182 | $71,703,555 | -$5,395,029 | $1.33 | 93 |
| 2022 Q3 | 57,306,752 | $89,403,802 | -$3,332,109 | $1.56 | 97 |
| 2022 Q2 | 59,291,260 | $91,305,115 | +$12,225,836 | $1.54 | 95 |
| 2022 Q1 | 50,404,861 | $129,034,768 | +$23,839,809 | $2.56 | 97 |
| 2021 Q4 | 40,971,724 | $120,062,000 | +$117,961,261 | $2.93 | 85 |
| 2021 Q3 | 704,170 | $1,725,000 | +$1,725,000 | $2.45 | 1 |