Xenon Pharmaceuticals Inc. - Common Stock (XENE)

CUSIP: 98420N105

Q4 2025 13F Holders as of 31 Dec 2025

Holder snapshot 7 signals
Share change
-594,096
Put/Call ratio
192%
SEC-reported price per share
$44.82
Number of holders
245
Value change
-$19,907,308
Number of buys
125
Open additional details 1 more signal available
Number of sells
95
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
95,032,800

Security key

98420N105

Report period

Q4 2025

Institutions

245

Top holders

10

Ownership snapshot

Top reported holders of XENE - Xenon Pharmaceuticals Inc. - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
BlackRock, Inc.
Disclosed value leader
FMR LLC
Comparable rows
15/15
Latest evidence
31 Dec 2025
13F 13D/G Lead comparable stake: 6.2% 13D/G row: BlackRock, Inc. Showing 1-6 of 15 holder rows.

Quick read

BlackRock, Inc. leads the comparable SEC ownership view at 6.2%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens BlackRock, Inc.'s linked filing trail.
Comparable ownership Top 5
BlackRock, Inc. 6.2%
DRIEHAUS CAPITAL MANAGEMENT LLC 4.9%
FMR LLC 9.4%
Avoro Capital Advisors LLC 5.7%
Janus Henderson Group Ltd. 4.2%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
BlackRock, Inc.
13F 13D/G
Company
6.2%
from 13D/G
$191,553,697
4,770,951 shares
30 Sep 2025
DRIEHAUS CAPITAL MANAGEMENT LLC
13D/G 13F
Company
4.9%
$255,350,473
4,491,653 shares
$0 31 Dec 2025
FMR LLC
13F
Company
13F
9.4%
$358,094,116
8,918,907 shares
30 Sep 2025
Avoro Capital Advisors LLC
13F
Company
13F
5.7%
$216,810,000
5,400,000 shares
30 Sep 2025
Janus Henderson Group Ltd.
13F
Company
13F
4.2%
$158,311,659
3,943,885 shares
30 Sep 2025
WELLINGTON MANAGEMENT GROUP LLP
13F
Company
13F
3.8%
$144,935,758
3,609,857 shares
30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
245
Shares
84,413,479
Rows available
245
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
218
Q4 2025 holders
245
Holder diff
27
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 value Q4 2025 value Value change Value Chg %
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