| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| ARMISTICE CAPITAL, LLC | 7.57% | -22.8% | $19,614,000 | -$5,772,120 | 4,200,000 | -22.7% | Armistice Capital, LLC | 30 Sep 2025 |
| EcoR1 Capital, LLC | 6.8% | $18,696,980 | 4,003,636 | EcoR1 Capital, LLC | 30 Sep 2025 | |||
| BlackRock, Inc. | 6.4% | $12,445,128 | 3,525,532 | BlackRock, Inc. | 31 Mar 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 30,211,020 | $141,111,218 | -$12,466,237 | $4.67 | 114 |
| 2025 Q2 | 33,174,673 | $103,118,305 | -$5,022,778 | $3.11 | 107 |
| 2025 Q1 | 34,693,910 | $117,319,204 | -$2,380,756 | $3.38 | 114 |
| 2024 Q4 | 34,577,603 | $195,996,497 | -$3,226,096 | $5.67 | 130 |
| 2024 Q3 | 35,034,671 | $205,128,146 | -$20,241,650 | $5.85 | 126 |
| 2024 Q2 | 38,132,801 | $301,619,686 | +$18,919,346 | $7.91 | 126 |
| 2024 Q1 | 35,559,200 | $331,104,508 | +$80,441,114 | $9.31 | 132 |
| 2023 Q4 | 26,951,934 | $227,544,384 | -$3,558,359 | $8.44 | 107 |
| 2023 Q3 | 27,251,321 | $211,188,846 | +$537,246 | $7.75 | 111 |
| 2023 Q2 | 26,875,646 | $307,720,979 | +$48,627,840 | $11.45 | 106 |
| 2023 Q1 | 23,842,811 | $183,821,375 | -$454,983 | $7.71 | 82 |
| 2022 Q4 | 23,994,562 | $146,245,078 | -$700,357 | $6.10 | 69 |
| 2022 Q3 | 24,135,758 | $142,907,865 | +$347,568 | $5.92 | 67 |
| 2022 Q2 | 24,076,804 | $142,325,318 | +$7,681,335 | $5.91 | 74 |
| 2022 Q1 | 22,468,342 | $171,312,566 | +$28,627,560 | $7.62 | 67 |
| 2021 Q4 | 18,846,543 | $51,240,128 | -$8,744,189 | $2.71 | 52 |
| 2021 Q3 | 22,241,759 | $58,623,539 | -$4,030,195 | $2.63 | 63 |
| 2021 Q2 | 23,442,885 | $96,817,913 | -$15,060,885 | $4.13 | 72 |
| 2021 Q1 | 26,694,047 | $125,738,812 | -$5,939,201 | $4.71 | 94 |
| 2020 Q4 | 27,690,758 | $198,031,668 | -$6,797,504 | $7.15 | 95 |
| 2020 Q3 | 28,071,762 | $299,694,014 | -$21,155,353 | $10.67 | 107 |
| 2020 Q2 | 29,835,329 | $376,668,426 | -$3,115,117 | $12.62 | 108 |
| 2020 Q1 | 30,273,841 | $276,907,152 | -$8,724,603 | $9.15 | 116 |
| 2019 Q4 | 30,853,647 | $429,835,458 | -$4,780,916 | $13.95 | 134 |
| 2019 Q3 | 30,673,858 | $527,882,858 | +$3,530,435 | $17.21 | 129 |
| 2019 Q2 | 29,288,476 | $796,370,599 | +$141,852,717 | $27.22 | 124 |
| 2019 Q1 | 27,472,078 | $525,823,405 | +$8,007,882 | $19.14 | 110 |
| 2018 Q4 | 27,858,099 | $261,831,496 | -$17,131,000 | $9.40 | 114 |
| 2018 Q3 | 28,912,415 | $547,055,271 | -$4,047,273 | $18.92 | 117 |
| 2018 Q2 | 29,099,816 | $568,637,489 | +$41,402,106 | $19.54 | 124 |
| 2018 Q1 | 27,065,667 | $508,508,214 | +$36,985,561 | $18.79 | 107 |
| 2017 Q4 | 25,186,321 | $418,085,441 | +$68,360,039 | $16.60 | 98 |
| 2017 Q3 | 11,312,957 | $232,911,475 | +$24,126,972 | $20.59 | 74 |
| 2017 Q2 | 10,949,052 | $98,104,354 | -$1,702,259 | $8.96 | 52 |
| 2017 Q1 | 11,060,819 | $146,442,646 | +$8,714,480 | $13.24 | 46 |
| 2016 Q4 | 10,954,007 | $139,545,784 | +$4,079,335 | $12.74 | 55 |
| 2016 Q3 | 10,637,831 | $127,760,820 | +$781,532 | $12.01 | 50 |
| 2016 Q2 | 10,598,201 | $116,470,479 | +$5,910,371 | $10.99 | 48 |
| 2016 Q1 | 10,015,808 | $86,972,821 | -$3,380,554 | $8.73 | 41 |
| 2015 Q4 | 10,403,150 | $225,137,498 | +$219,950,498 | $21.90 | 35 |