| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FMR LLC | 8.3% | $239,585,319 | 7,964,937 | FMR LLC | 30 Sep 2025 | |||
| BlackRock, Inc. | 5.1% | $183,098,959 | 4,820,931 | BlackRock, Inc. | 31 Mar 2025 | |||
| SANDS CAPITAL MANAGEMENT, LLC | 4.7% | $163,238,154 | 4,298,003 | SANDS CAPITAL MANAGEMENT, LLC | 31 Dec 2024 | |||
| WELLINGTON MANAGEMENT GROUP LLP | 2.7% | $93,337,483 | 2,457,543 | Wellington Management Group LLP | 31 Dec 2024 |
As of 30 Sep 2025, 296 institutional investors reported holding 95,480,234 shares of Ultragenyx Pharmaceutical Inc. - COMMON STOCK (RARE). This represents 99% of the company’s total 95,963,102 outstanding shares.
The largest institutional shareholders of Ultragenyx Pharmaceutical Inc. - COMMON STOCK (RARE) together control 68% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 11% | 10,132,728 | -0.79% | 0% | $304,792,459 |
| FMR LLC | 7.6% | 7,283,296 | +180% | 0.01% | $219,081,558 |
| BlackRock, Inc. | 6.7% | 6,425,263 | +2.7% | 0% | $193,271,911 |
| JPMORGAN CHASE & CO | 4.2% | 4,011,429 | +23% | 0.01% | $120,663,796 |
| SANDS CAPITAL MANAGEMENT, LLC | 3.9% | 3,769,853 | -4.4% | 0.31% | $113,397,178 |
| STATE STREET CORP | 3.8% | 3,692,487 | +44% | 0% | $111,070,009 |
| RTW INVESTMENTS, LP | 3.4% | 3,258,266 | +91% | 1.2% | $98,008,641 |
| BAKER BROS. ADVISORS LP | 2.9% | 2,772,692 | 0% | 0.6% | $83,402,575 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.4% | 2,310,174 | -20% | 0.01% | $69,491,000 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 2.3% | 2,167,729 | +614% | 0.26% | $65,205,288 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2.1% | 2,019,000 | -11% | 1.8% | $60,731,520 |
| WELLINGTON MANAGEMENT GROUP LLP | 2% | 1,945,129 | +3.9% | 0.01% | $58,509,481 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 1,580,507 | -7.7% | 0% | $47,551,518 |
| DEUTSCHE BANK AG\ | 1.6% | 1,546,101 | -7.2% | 0.02% | $46,506,718 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1.6% | 1,545,279 | +6.4% | 0.12% | $46,482,000 |
| Pictet Asset Management Holding SA | 1.5% | 1,458,187 | -14% | 0.04% | $43,988,784 |
| Rock Springs Capital Management LP | 1.3% | 1,246,341 | -10% | 2.2% | $37,489,937 |
| GW&K Investment Management, LLC | 1.2% | 1,150,169 | +139% | 0.31% | $34,597,000 |
| Schonfeld Strategic Advisors LLC | 1.2% | 1,144,589 | +102% | 0.24% | $34,429,232 |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 1.1% | 1,069,098 | +103% | 0.29% | $32,158,463 |
| Frazier Life Sciences Management, L.P. | 1% | 983,715 | 0% | 0.89% | $29,590,147 |
| Aberdeen Group plc | 1% | 973,656 | +94% | 0.05% | $29,287,572 |
| MORGAN STANLEY | 0.95% | 910,183 | +42% | 0% | $27,378,343 |
| Russell Investments Group, Ltd. | 0.88% | 840,451 | +599% | 0.03% | $25,280,799 |
| Invesco Ltd. | 0.83% | 794,849 | +9.8% | 0% | $23,909,058 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 2,189,482 | $50,320,060 | +$2,731,931 | $23.00 | 17 |
| 2025 Q3 | 95,480,234 | $2,872,312,808 | -$30,046,954 | $30.08 | 296 |
| 2025 Q2 | 94,131,376 | $3,423,160,510 | +$191,188,547 | $36.36 | 307 |
| 2025 Q1 | 88,841,861 | $3,218,915,813 | +$30,616,617 | $36.21 | 297 |
| 2024 Q4 | 87,497,812 | $3,681,153,433 | +$1,949,206 | $42.07 | 309 |
| 2024 Q3 | 86,896,233 | $4,824,969,188 | -$72,319,917 | $55.55 | 299 |
| 2024 Q2 | 88,212,580 | $3,625,598,894 | +$337,028,289 | $41.10 | 273 |
| 2024 Q1 | 79,925,459 | $3,729,060,008 | -$19,184,689 | $46.69 | 268 |
| 2023 Q4 | 80,397,353 | $3,844,802,509 | +$498,492,380 | $47.82 | 236 |
| 2023 Q3 | 70,612,041 | $2,517,056,820 | +$10,459,486 | $35.65 | 219 |
| 2023 Q2 | 69,514,116 | $3,206,303,623 | +$38,331,356 | $46.13 | 239 |
| 2023 Q1 | 68,735,803 | $2,755,924,776 | +$28,159,264 | $40.10 | 227 |
| 2022 Q4 | 68,068,127 | $3,153,029,340 | +$13,205,113 | $46.33 | 225 |
| 2022 Q3 | 67,920,512 | $2,812,302,784 | -$149,070,496 | $41.41 | 223 |
| 2022 Q2 | 67,540,585 | $4,030,154,883 | +$24,063,212 | $59.66 | 210 |
| 2022 Q1 | 67,087,441 | $4,870,684,649 | -$37,258,962 | $72.62 | 227 |
| 2021 Q4 | 67,646,883 | $5,688,385,130 | +$80,515,709 | $84.09 | 224 |
| 2021 Q3 | 66,666,465 | $6,012,124,489 | +$97,920,619 | $90.19 | 217 |
| 2021 Q2 | 65,481,898 | $6,240,143,536 | -$246,149,121 | $95.35 | 235 |
| 2021 Q1 | 67,877,270 | $7,730,039,829 | +$45,641,218 | $113.86 | 244 |
| 2020 Q4 | 67,658,657 | $9,366,525,048 | +$640,902,584 | $138.43 | 247 |
| 2020 Q3 | 63,092,193 | $5,187,430,003 | -$8,503,385 | $82.19 | 199 |
| 2020 Q2 | 63,208,158 | $4,944,359,312 | +$242,670,060 | $78.22 | 185 |
| 2020 Q1 | 60,196,473 | $2,674,187,064 | +$87,973,460 | $44.43 | 166 |
| 2019 Q4 | 57,960,233 | $2,475,997,749 | -$30,518,994 | $42.71 | 162 |
| 2019 Q3 | 58,743,550 | $2,513,000,802 | -$3,746,657 | $42.78 | 164 |
| 2019 Q2 | 58,918,990 | $3,740,916,935 | +$48,975,164 | $63.50 | 165 |
| 2019 Q1 | 58,332,415 | $4,045,800,203 | +$544,963,218 | $69.36 | 170 |
| 2018 Q4 | 50,637,251 | $2,201,420,429 | -$8,455,097 | $43.48 | 155 |
| 2018 Q3 | 49,753,360 | $3,798,517,088 | +$72,495,753 | $76.34 | 171 |
| 2018 Q2 | 48,810,187 | $3,751,960,915 | +$16,214,593 | $76.87 | 151 |
| 2018 Q1 | 48,941,898 | $2,495,515,451 | +$366,583,930 | $50.99 | 159 |
| 2017 Q4 | 43,222,558 | $2,004,746,148 | +$107,302,956 | $46.38 | 154 |
| 2017 Q3 | 40,596,743 | $2,164,481,778 | -$37,427,143 | $53.26 | 148 |
| 2017 Q2 | 41,247,736 | $2,557,116,579 | +$26,416,443 | $62.11 | 154 |
| 2017 Q1 | 40,725,846 | $2,759,699,220 | +$146,474,004 | $67.78 | 160 |
| 2016 Q4 | 41,627,417 | $2,926,846,973 | +$146,410,374 | $70.31 | 172 |
| 2016 Q3 | 39,527,653 | $2,802,274,760 | +$175,377,803 | $70.94 | 167 |
| 2016 Q2 | 36,785,323 | $1,799,227,912 | -$45,286,683 | $48.91 | 153 |
| 2016 Q1 | 37,365,438 | $2,365,011,412 | +$86,675,812 | $63.31 | 159 |
| 2015 Q4 | 35,576,368 | $3,991,057,622 | +$35,682,868 | $112.18 | 165 |
| 2015 Q3 | 35,309,662 | $3,400,791,001 | +$270,511,040 | $96.31 | 156 |
| 2015 Q2 | 32,519,914 | $3,330,261,876 | +$95,161,030 | $102.39 | 150 |
| 2015 Q1 | 31,628,609 | $1,962,983,846 | +$227,346,470 | $62.09 | 126 |
| 2014 Q4 | 27,930,073 | $1,225,534,642 | +$58,809,022 | $43.88 | 98 |
| 2014 Q3 | 26,496,419 | $1,499,696,849 | +$542,429,017 | $56.60 | 98 |
| 2014 Q2 | 16,922,876 | $747,921,361 | +$55,850,290 | $44.89 | 81 |
| 2014 Q1 | 15,678,184 | $746,820,000 | +$746,820,000 | $48.89 | 77 |