TScan Therapeutics, Inc. - Voting Common Stock, par value $0.0001 per share (TCRX) Institutional Ownership

13F Institutional Holders and Ownership History from Q3 2021 to Q4 2025

Type / Class
Equity / Voting Common Stock, par value $0.0001 per share
Symbol
TCRX on Nasdaq
Shares outstanding
52,382,313
Price per share
$1.04
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
30,668,719
Total reported value
$30,666,797
% of total 13F portfolios
0%
Share change
-3,786,971
Value change
-$7,264,797
Number of holders
58
Price from insider filings
$1.04
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of TScan Therapeutics, Inc. - Voting Common Stock, par value $0.0001 per share (TCRX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Lynx1 Capital Management LP 15% +37% $11,393,153 +$3,625,000 7,857,347 +47% Lynx1 Capital Management LP 30 Jun 2025
BIOTECHNOLOGY VALUE FUND L P 10% $8,421,666 5,263,541 BVF PARTNERS L P/IL 31 Mar 2025
K2 HealthVentures Equity Trust LLC 6.9% $5,764,320 3,602,700 K2 HealthVentures Equity Trust LLC 31 Dec 2024
ADAGE CAPITAL PARTNERS GP, L.L.C. 7.1% $5,600,000 3,500,000 Adage Capital Management, L.P. 31 Dec 2024
Adage Capital Management, L.P. 2.5% $1,957,500 1,350,000 Adage Capital Management, L.P. 30 Jun 2025
BlackRock, Inc. 1.8% -72% $1,475,894 -$2,875,873 958,373 -66% BlackRock, Inc. 30 Jun 2025
EcoR1 Capital, LLC 1.3% $1,060,533 662,833 EcoR1 Capital, LLC 31 Mar 2025

As of 31 Dec 2025, 58 institutional investors reported holding 30,668,719 shares of TScan Therapeutics, Inc. - Voting Common Stock, par value $0.0001 per share (TCRX). This represents 59% of the company’s total 52,382,313 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of TScan Therapeutics, Inc. - Voting Common Stock, par value $0.0001 per share (TCRX) together control 57% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Lynx1 Capital Management LP 15% 8,019,148 +2.1% 1.6% $8,019,148
BVF INC/IL 10% 5,226,074 0% 0.18% $5,226,074
BAKER BROS. ADVISORS LP 5.3% 2,784,792 0% 0.02% $2,784,792
VANGUARD GROUP INC 4.7% 2,475,733 +6.8% 0% $2,475,733
BlackRock, Inc. 3.5% 1,848,695 -22% 0% $1,848,695
Aberdeen Group plc 3.4% 1,785,241 +32% 0% $1,785,241
Deer Management Co. LLC 2.4% 1,245,504 0% 0.12% $1,245,504
RENAISSANCE TECHNOLOGIES LLC 2.2% 1,141,069 +37% 0% $1,141,069
TWO SIGMA INVESTMENTS, LP 1.2% 651,179 +55% 0% $651,179
DC Funds, LP 1.2% 630,000 0% 43% $630,000
GEODE CAPITAL MANAGEMENT, LLC 1.1% 562,153 -0.97% 0% $562,360
MILLENNIUM MANAGEMENT LLC 0.77% 403,618 -13% 0% $403,618
JANE STREET GROUP, LLC 0.74% 388,284 +378% 0% $388,284
TWO SIGMA ADVISERS, LP 0.68% 353,900 +23% 0% $353,900
MARSHALL WACE, LLP 0.65% 339,240 +628% 0% $339,240
GSA CAPITAL PARTNERS LLP 0.43% 226,164 0.02% $226,000
MORGAN STANLEY 0.43% 225,829 -73% 0% $225,829
XTX Topco Ltd 0.42% 219,001 +1142% 0.01% $219,001
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.41% 216,133 +171% 0% $216,133
STATE STREET CORP 0.4% 207,313 +5.1% 0% $207,313
JACOBS LEVY EQUITY MANAGEMENT, INC 0.36% 188,152 0% $188,152
CITADEL ADVISORS LLC 0.31% 162,877 -58% 0% $162,877
BROWN BROTHERS HARRIMAN & CO 0.27% 143,051 0% 0% $143,051
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.22% 115,400 -18% 0% $115,400
NORTHERN TRUST CORP 0.19% 98,198 -0.36% 0% $98,198

Institutional Holders of TScan Therapeutics, Inc. - Voting Common Stock, par value $0.0001 per share (TCRX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 30,668,719 $30,666,797 -$7,264,797 $1.00 58
2025 Q3 34,601,160 $62,910,264 -$1,894,623 $1.82 72
2025 Q2 35,724,879 $51,820,655 -$5,881,550 $1.45 79
2025 Q1 40,135,840 $55,389,702 -$2,855,488 $1.38 92
2024 Q4 41,522,755 $126,231,784 -$5,917,073 $3.04 87
2024 Q3 41,835,445 $208,343,506 +$256,552 $4.98 86
2024 Q2 41,438,662 $242,461,718 +$40,505,361 $5.85 78
2024 Q1 34,291,369 $272,339,183 +$19,079,789 $7.94 65
2023 Q4 31,912,819 $186,051,742 +$7,213,515 $5.83 54
2023 Q3 28,588,231 $73,196,468 +$2,177,876 $2.56 32
2023 Q2 27,951,619 $69,879,871 +$45,817,232 $2.50 28
2023 Q1 9,667,555 $20,309,551 +$609,616 $2.10 28
2022 Q4 9,519,305 $14,788,379 -$121,391 $1.55 28
2022 Q3 9,508,092 $29,003,732 -$530,741 $3.05 24
2022 Q2 9,682,082 $30,449,817 +$1,528,632 $3.14 23
2022 Q1 9,407,022 $26,340,000 -$1,500,189 $2.80 24
2021 Q4 9,861,945 $44,380,000 -$2,457,435 $4.50 28
2021 Q3 9,504,939 $78,230,000 +$78,229,998 $8.34 25