Tectonic Therapeutic, Inc. - Common Stock, $0.0001 par value per share (TECX) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2024 to Q4 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
TECX on Nasdaq
Shares outstanding
18,718,426
Price per share
$20.69
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
13,814,358
Total reported value
$288,147,446
% of total 13F portfolios
0%
Share change
+1,623,517
Value change
+$44,894,652
Number of holders
105
Price from insider filings
$20.69
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Tectonic Therapeutic, Inc. - Common Stock, $0.0001 par value per share (TECX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
SPRINGER TIMOTHY A 32% +7.9% $96,537,428 +$1,958,250 4,313,558 +2.1% Timothy A. Springer 03 Apr 2025
FMR LLC 15% +47% $62,650,568 +$28,714,995 2,799,400 +85% FMR LLC 31 Mar 2025
Aberdeen Group plc 6.1% $23,818,449 1,141,824 Aberdeen Group plc 31 Dec 2025
MCGUIRE TERRANCE 6.3% 0% $14,725,503 -$11,190,022 657,976 -43% Terrance McGuire 03 Apr 2025

As of 31 Dec 2025, 105 institutional investors reported holding 13,814,358 shares of Tectonic Therapeutic, Inc. - Common Stock, $0.0001 par value per share (TECX). This represents 74% of the company’s total 18,718,426 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Tectonic Therapeutic, Inc. - Common Stock, $0.0001 par value per share (TECX) together control 67% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FMR LLC 15% 2,807,442 +0.02% 0% $58,563,233
Aberdeen Group plc 6.1% 1,141,824 +221% 0.04% $23,818,449
BRAIDWELL LP 5% 927,524 +26% 0.62% $19,348,151
BAKER BROS. ADVISORS LP 4.8% 903,400 +803% 0.11% $18,844,924
BlackRock, Inc. 4.6% 854,363 +3.2% 0% $17,822,013
5AM Venture Management, LLC 3.2% 606,660 +19% 4% $12,654,928
VANGUARD GROUP INC 3.2% 599,898 +5.3% 0% $12,513,872
ORBIMED ADVISORS LLC 3.1% 574,600 0.26% $11,986,156
Point72 Asset Management, L.P. 2.6% 492,332 +17% 0.02% $10,270,046
Vestal Point Capital, LP 1.8% 328,000 0.25% $6,842,080
CITADEL ADVISORS LLC 1.7% 317,617 +6.4% 0% $6,625,491
Bollard Group LLC 1.6% 302,953 0% 0.17% $6,320,000
MILLENNIUM MANAGEMENT LLC 1.6% 300,820 +26% 0% $6,275,105
GEODE CAPITAL MANAGEMENT, LLC 1.4% 263,560 -2.2% 0% $5,498,708
Pale Fire Capital SE 1.4% 261,026 +0.5% 0.7% $5,445,002
Prosight Management, LP 1.3% 235,000 -38% 1% $4,902,100
Opaleye Management Inc. 1.1% 214,747 0.6% $4,479,622
KENNEDY CAPITAL MANAGEMENT LLC 1.1% 209,225 +0.22% 0.09% $4,364,434
STATE STREET CORP 1.1% 209,125 +26% 0% $4,362,348
Woodline Partners LP 1.1% 200,000 0% 0.02% $4,172,000
Squarepoint Ops LLC 1.1% 199,646 +205% 0.01% $4,164,616
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.81% 151,713 0% $3,164,733
WELLS FARGO & COMPANY/MN 0.64% 120,411 +18% 0% $2,511,774
D. E. Shaw & Co., Inc. 0.64% 120,250 0% $2,508,415
ExodusPoint Capital Management, LP 0.59% 111,188 +754% 0.03% $2,319,382

Institutional Holders of Tectonic Therapeutic, Inc. - Common Stock, $0.0001 par value per share (TECX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 13,814,358 $288,147,446 +$44,894,652 $20.86 105
2025 Q3 12,105,071 $189,928,399 -$10,912,119 $15.69 99
2025 Q2 12,112,699 $240,681,548 +$18,199,970 $19.87 82
2025 Q1 11,227,627 $198,820,413 +$3,981,198 $17.71 78
2024 Q4 7,686,866 $354,905,739 +$30,548,457 $46.17 70
2024 Q3 7,175,807 $217,428,427 +$53,307,772 $30.30 52
2024 Q2 5,345,881 $88,045,301 +$88,041,200 $16.47 39