Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share (TSHA)

Q: What does CUSIP 877619106 represent in this 13F holders report?

CUSIP 877619106 is the security identifier for TSHA - Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share used to aggregate holder disclosures.

Q: How many institutions held TSHA - Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share in Q2 2025?

147 institutional investors reported TSHA - Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share for Q2 2025. Use the holders table for investor-level position and value details.

CUSIP: 877619106

Q2 2025 13F Holders as of 30 Jun 2025

Security type / class: Equity / Common Stock, par value $0.00001 per share
Total 13F shares: 257,684,976
Total 13F value: $595,324,582
Share change: +90,905,207
Put/Call ratio: 16%
SEC-reported price per share: $2.31
Number of holders: 147
Value change: +$211,768,578
Number of buys: 90
Number of sells: 53
Shares outstanding: 285,714,286

Security key

877619106

Report period

Q2 2025

Institutions

147

Top holders

TSHA full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2025 Previous quarter: Q1 2025 Taysha Gene Therapies, Inc. SEC filings Taysha Gene Therapies, Inc. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 877619106

Newer quarter: Q3 2025 Previous quarter: Q1 2025

Recent filing periods:

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024

Ownership snapshot

Top reported holders of TSHA - Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

Paul B. Manning

Disclosed value leader

Paul B. Manning

Comparable rows

15/15

Latest evidence

30 Jun 2025

13D/G 3/4/5 13F Lead comparable stake: 9.8% 13D/G row: Paul B. Manning Showing 1-6 of 15 holder rows.

Quick read

Paul B. Manning leads the comparable SEC ownership view at 9.8%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Paul B. Manning's linked filing trail.

Comparable ownership Top 5

Paul B. Manning 9.8%

MORGAN STANLEY 6.7%

GOLDMAN SACHS GROUP INC 5.1%

Avoro Capital Advisors LLC 7%

RTW INVESTMENTS, LP 6.6%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
Paul B. Manning	13D/G 3/4/5 10%+ Owner 13D/G 3/4/5	9.8%	$59,394,578 25,601,111 shares	$0	30 May 2025
MORGAN STANLEY	13D/G 13F Company 13D/G 13F	6.7%	$44,506,820 16,858,644 shares	-$2,034,437	30 Jun 2025
GOLDMAN SACHS GROUP INC	13D/G 13F THE GOLDMAN SACHS GROUP, INC. · Company 13D/G 13F	5.1%	$33,274,806 12,748,968 shares	$0	26 Jun 2025
Avoro Capital Advisors LLC	13F Company 13F	7%	$27,799,999 19,999,999 shares	—	31 Mar 2025
RTW INVESTMENTS, LP	13F Company 13F	6.6%	$26,115,134 18,787,866 shares	—	31 Mar 2025
FMR LLC	13F Company 13F	5.5%	$21,728,416 15,631,954 shares	—	31 Mar 2025

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q2 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

147

257,684,976

Rows available

147

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q2 2025 vs Q1 2025 Across Filers

Q1 2025 holders

124

Q2 2025 holders

147

Holder diff

Investor	Q1 2025 Shares	Q2 2025 Shares	Share Diff	Share Chg %	Q1 2025 value	Q2 2025 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend