Security key
877619106
Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share (TSHA)
CUSIP: 877619106
Q2 2025 13F Holders as of 30 Jun 2025
- Type / Class
- Equity / Common Stock, par value $0.00001 per share
- Shares outstanding
- 285,714,286
- Total 13F shares
- 257,684,976
- Share change
- +90,905,207
- Total reported value
- $595,324,582
- Put/Call ratio
- 16%
- Price per share
- $2.31
- Number of holders
- 147
- Value change
- +$211,768,578
- Number of buys
- 90
- Number of sells
- 53
Report period
Q2 2025
Institutions
147
Top holders
10
TSHA full security history
Newer quarter: Q3 2025
Previous quarter: Q1 2025
Taysha Gene Therapies, Inc. SEC filings
Taysha Gene Therapies, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 877619106
Recent filing periods:
Top shareholders of TSHA - Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Paul B. Manning |
13D/G
3/4/5
|
10%+ Owner |
9.8%
|
25,601,111
|
$59,394,578 | $0 | 30 May 2025 | |
| MORGAN STANLEY |
13D/G
13F
|
Company |
6.7%
|
16,858,644
|
$44,506,820 | -$2,034,437 | 30 Jun 2025 | |
| GOLDMAN SACHS GROUP INC |
13D/G
13F
|
THE GOLDMAN SACHS GROUP, INC. · Company |
5.1%
|
12,748,968
|
$33,274,806 | $0 | 26 Jun 2025 | |
| Avoro Capital Advisors LLC |
13F
|
Company |
7%
|
19,999,999
|
$27,799,999 | — | 31 Mar 2025 | |
| RTW INVESTMENTS, LP |
13F
|
Company |
6.6%
|
18,787,866
|
$26,115,134 | — | 31 Mar 2025 | |
| FMR LLC |
13F
|
Company |
5.5%
|
15,631,954
|
$21,728,416 | — | 31 Mar 2025 | |
| BlackRock, Inc. |
13F
|
Company |
4.8%
|
13,589,178
|
$18,888,958 | — | 31 Mar 2025 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
|
Company |
3.8%
|
10,872,503
|
$15,112,779 | — | 31 Mar 2025 | |
| Octagon Capital Advisors LP |
13F
|
Company |
3.7%
|
10,700,000
|
$14,873,000 | — | 31 Mar 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
3.1%
|
8,770,921
|
$12,191,580 | — | 31 Mar 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
2.3%
|
6,514,737
|
$9,055,484 | — | 31 Mar 2025 | |
| Point72 Asset Management, L.P. |
13F
|
Company |
1.6%
|
4,569,678
|
$6,351,852 | — | 31 Mar 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
1.4%
|
4,004,756
|
$5,566,611 | — | 31 Mar 2025 | |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD |
13F
|
Company |
1.3%
|
3,700,000
|
$5,143,000 | — | 31 Mar 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.3%
|
3,664,732
|
$5,095,347 | — | 31 Mar 2025 | |
| STATE STREET CORP |
13F
|
Company |
1.1%
|
3,233,512
|
$4,494,582 | — | 31 Mar 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
1%
|
3,000,000
|
$4,170,000 | — | 31 Mar 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.62%
|
1,772,654
|
$2,463,989 | — | 31 Mar 2025 | |
| Granahan Investment Management, LLC |
13F
|
Company |
0.57%
|
1,640,793
|
$2,280,702 | — | 31 Mar 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.5%
|
1,431,666
|
$1,990,015 | — | 31 Mar 2025 | |
| Palo Alto Investors LP |
13F
|
Company |
0.5%
|
1,419,468
|
$1,973,061 | — | 31 Mar 2025 | |
| B Group, Inc. |
13F
|
Company |
0.44%
|
1,255,556
|
$1,745,223 | — | 31 Mar 2025 | |
| ADAR1 Capital Management, LLC |
13F
|
Company |
0.37%
|
1,066,309
|
$1,482,170 | — | 31 Mar 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.35%
|
1,003,067
|
$1,394,263 | — | 31 Mar 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.3%
|
858,254
|
$1,192,973 | — | 31 Mar 2025 | |
| Quantum Private Wealth, LLC |
13F
|
Company |
0.28%
|
791,476
|
$1,100,152 | — | 31 Mar 2025 | |
| SUPERSTRING CAPITAL MANAGEMENT LP |
13F
|
Company |
0.26%
|
755,599
|
$1,050,283 | — | 31 Mar 2025 | |
| Sands Capital Alternatives, LLC |
13F
|
Company |
0.25%
|
724,873
|
$1,007,573 | — | 31 Mar 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.25%
|
708,966
|
$985,463 | — | 31 Mar 2025 | |
| Alphabet Inc. |
13F
|
Company |
0.22%
|
640,882
|
$890,826 | — | 31 Mar 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.22%
|
636,842
|
$885,211 | — | 31 Mar 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
0.22%
|
625,198
|
$869,025 | — | 31 Mar 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.19%
|
547,128
|
$760,508 | — | 31 Mar 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.19%
|
546,414
|
$759,516 | — | 31 Mar 2025 | |
| DAFNA Capital Management LLC |
13F
|
Company |
0.18%
|
522,500
|
$726,275 | — | 31 Mar 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.16%
|
453,420
|
$630,254 | — | 31 Mar 2025 | |
| UBS Group AG |
13F
|
Company |
0.15%
|
418,132
|
$581,204 | — | 31 Mar 2025 | |
| NorthCoast Asset Management LLC |
13F
|
Company |
0.1%
|
292,778
|
$406,961 | — | 31 Mar 2025 | |
| Jefferies Financial Group Inc. |
13F
|
Company |
0.09%
|
245,254
|
$340,903 | — | 31 Mar 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.08%
|
227,472
|
$316,186 | — | 31 Mar 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.08%
|
216,611
|
$301,089 | — | 31 Mar 2025 | |
| RHUMBLINE ADVISERS |
13F
|
Company |
0.07%
|
205,462
|
$285,584 | — | 31 Mar 2025 | |
| XTX Topco Ltd |
13F
|
Company |
0.07%
|
203,129
|
$282,349 | — | 31 Mar 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.06%
|
159,899
|
$222,259 | — | 31 Mar 2025 | |
| LOS ANGELES CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.05%
|
142,810
|
$198,506 | — | 31 Mar 2025 | |
| HRT FINANCIAL LP |
13F
|
Company |
0.05%
|
139,692
|
$194,000 | — | 31 Mar 2025 | |
| EntryPoint Capital, LLC |
13F
|
Company |
0.05%
|
135,897
|
$188,897 | — | 31 Mar 2025 | |
| Privium Fund Management B.V. |
13F
|
Company |
0.05%
|
134,900
|
$187,511 | — | 31 Mar 2025 | |
| DEUTSCHE BANK AG\ |
13F
|
Company |
0.05%
|
134,418
|
$186,841 | — | 31 Mar 2025 | |
| CITIGROUP INC |
13F
|
Company |
0.05%
|
133,194
|
$185,140 | — | 31 Mar 2025 |
Institutional Holders of Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share (TSHA) as of Q2 2025
As of 30 Jun 2025,
Taysha Gene Therapies, Inc. - Common Stock, par value $0.00001 per share (TSHA) was held by
147 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
257,684,976 shares.
The largest 10 holders included
RTW INVESTMENTS, LP, RA CAPITAL MANAGEMENT, L.P., Avoro Capital Advisors LLC, MORGAN STANLEY, FMR LLC, BlackRock, Inc., Octagon Capital Advisors LP, GOLDMAN SACHS GROUP INC, Siren, L.L.C., and VANGUARD GROUP INC.
This page lists
149
institutional shareholders reporting positions in this security
for the Q2 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q2 2025 vs Q1 2025 Across Filers
Q1 2025 holders
124
Q2 2025 holders
147
Holder diff
23
| Investor | Q1 2025 Shares | Q2 2025 Shares | Share Diff | Share Chg % | Q1 2025 Value $ | Q2 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.