How many institutions held SYRS - Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value in Q4 2021?

84 institutional investors reported SYRS - Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value for Q4 2021. Use the holders table for investor-level position and value details.

Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value (SYRS)

Q: What does CUSIP 87184Q107 represent in this 13F holders report?

CUSIP 87184Q107 is the security identifier for SYRS - Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value used to aggregate holder disclosures.

CUSIP: 87184Q107

Q4 2021 13F Holders as of 31 Dec 2021

Type / Class: Equity / Common Stock, $0.001 par value
Shares outstanding: 27,995,500
Total 13F shares: 51,167,771
Share change: +1,054,821
Total reported value: $165,935,422
Put/Call ratio: 398%
Price per share: $3.26
Number of holders: 84
Value change: +$2,424,541
Number of buys: 35
Number of sells: 50

Quarterly Holders Quick Answers

What is CUSIP 87184Q107?
CUSIP 87184Q107 identifies SYRS - Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value in SEC institutional holdings data.

Need full ownership history?
Open the full security ownership history page.

Next holder-history checks

These links keep the next click tied to holder verification, nearby quarters, or outside-13F ownership context.

Back to full security ownership history for the broader multi-quarter picture.
Latest 13F filings for newly reported positions across managers.
Latest Schedule 13D/13G reports for ownership changes outside the 13F cadence.
SEC investors directory for manager drilldown.

Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2022
Previous quarter: Q3 2021

Recent filing periods for CUSIP 87184Q107:

Q2 2023 Q1 2023 Q4 2022 Q3 2022 Q2 2022 Q1 2022 Q4 2021 Q3 2021

Top shareholders of SYRS - Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	32%	9,058,845	$40,493,000	—	30 Sep 2021	13F
Bain Capital Life Sciences Investors, LLC	13F	Company	21%	5,785,036	$25,859,000	—	30 Sep 2021	13F
BlackRock Finance, Inc.	13F	Company	16%	4,353,672	$19,461,000	—	30 Sep 2021	13F
Ally Bridge Group (NY) LLC	13F	Company	12%	3,439,895	$15,376,000	—	30 Sep 2021	13F
VANGUARD GROUP INC	13F	Company	11%	2,985,978	$13,348,000	—	30 Sep 2021	13F
Omega Fund Management, LLC	13F	Company	9%	2,512,705	$11,232,000	—	30 Sep 2021	13F
Artal Group S.A.	13F	Company	7.1%	2,000,000	$8,940,000	—	30 Sep 2021	13F
Samsara BioCapital, LLC	13F	Company	7.8%	2,189,199	$8,624,000	—	30 Sep 2021	13F
ORBIMED ADVISORS LLC	13F	Company	6.6%	1,837,500	$8,214,000	—	30 Sep 2021	13F
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F	Company	6.4%	1,800,000	$8,046,000	—	30 Sep 2021	13F
Altium Capital Management LLC	13F	Company	4.5%	1,272,412	$5,688,000	—	30 Sep 2021	13F
STATE STREET CORP	13F	Company	4%	1,115,572	$4,987,000	—	30 Sep 2021	13F
Sio Capital Management, LLC	13F	Company	3.2%	900,677	$4,026,000	—	30 Sep 2021	13F
RA CAPITAL MANAGEMENT, L.P.	13F	Company	3.2%	900,000	$4,023,000	—	30 Sep 2021	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	3.1%	857,646	$3,833,000	—	30 Sep 2021	13F
S.c.a. Candriam	13F	Individual	2.1%	584,272	$2,612,000	—	30 Sep 2021	13F
NORTHERN TRUST CORP	13F	Company	1.9%	524,679	$2,345,000	—	30 Sep 2021	13F
GOLDMAN SACHS GROUP INC	13F	Company	1.8%	490,501	$2,192,000	—	30 Sep 2021	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	1.1%	316,375	$1,414,000	—	30 Sep 2021	13F
LOS ANGELES CAPITAL MANAGEMENT LLC	13F	Company	0.92%	258,938	$1,157,000	—	30 Sep 2021	13F
MORGAN STANLEY	13F	Company	0.82%	229,325	$1,025,000	—	30 Sep 2021	13F
Nuveen Asset Management, LLC	13F	Company	0.71%	198,578	$1,009,000	—	30 Sep 2021	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	0.76%	213,253	$953,000	—	30 Sep 2021	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.73%	205,303	$918,000	—	30 Sep 2021	13F
Bank of New York Mellon Corp	13F	Company	0.7%	196,145	$876,000	—	30 Sep 2021	13F
MARSHALL WACE, LLP	13F	Company	0.66%	183,451	$820,000	—	30 Sep 2021	13F
TWO SIGMA ADVISERS, LP	13F	Company	0.62%	172,700	$772,000	—	30 Sep 2021	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.51%	142,790	$639,000	—	30 Sep 2021	13F
GSA CAPITAL PARTNERS LLP	13F	Company	0.39%	110,337	$493,000	—	30 Sep 2021	13F
Connor, Clark & Lunn Investment Management Ltd.	13F	Company	0.37%	103,307	$462,000	—	30 Sep 2021	13F
JACOBS LEVY EQUITY MANAGEMENT, INC	13F	Company	0.36%	101,646	$454,000	—	30 Sep 2021	13F
Ensign Peak Advisors, Inc	13F	Company	0.36%	100,000	$447,000	—	30 Sep 2021	13F
PDT Partners, LLC	13F	Company	0.34%	96,084	$429,000	—	30 Sep 2021	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.33%	91,278	$408,000	—	30 Sep 2021	13F
Assenagon Asset Management S.A.	13F	Company	0.31%	87,073	$389,000	—	30 Sep 2021	13F
Cubist Systematic Strategies, LLC	13F	Company	0.31%	86,990	$389,000	—	30 Sep 2021	13F
Palo Alto Investors LP	13F	Company	0.29%	80,600	$360,000	—	30 Sep 2021	13F
JANE STREET GROUP, LLC	13F	Company	0.28%	78,610	$352,000	—	30 Sep 2021	13F
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	13F	Company	0.28%	78,535	$351,000	—	30 Sep 2021	13F
ALPS ADVISORS INC	13F	Company	0.27%	75,904	$339,000	—	30 Sep 2021	13F
CITADEL ADVISORS LLC	13F	Company	0.25%	69,528	$311,000	—	30 Sep 2021	13F
RHUMBLINE ADVISERS	13F	Company	0.24%	66,771	$298,000	—	30 Sep 2021	13F
FRANKLIN RESOURCES INC	13F	Company	0.23%	64,000	$286,000	—	30 Sep 2021	13F
DEUTSCHE BANK AG\	13F	Company	0.21%	59,973	$268,000	—	30 Sep 2021	13F
STATE OF WISCONSIN INVESTMENT BOARD	13F	Company	0.21%	59,747	$267,000	—	30 Sep 2021	13F
SIMPLEX TRADING, LLC	13F	Company	0.16%	45,117	$255,000	—	30 Sep 2021	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	0.2%	55,900	$250,000	—	30 Sep 2021	13F
ACT CAPITAL MANAGEMENT, LLC	13F	Company	0.19%	52,500	$235,000	—	30 Sep 2021	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	0.18%	49,084	$219,000	—	30 Sep 2021	13F
LPL Financial LLC	13F	Company	0.17%	47,115	$211,000	—	30 Sep 2021	13F

Institutional Holders of Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value (SYRS) as of Q4 2021

As of 31 Dec 2021, Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value (SYRS) was held by 84 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 51,167,771 shares. The largest 10 holders included FMR LLC, Bain Capital Life Sciences Investors, LLC, BlackRock Inc., Ally Bridge Group (NY) LLC, Artal Group S.A., Flagship Pioneering Inc., VANGUARD GROUP INC, Omega Fund Management, LLC, Samsara BioCapital, LLC, and ADAGE CAPITAL PARTNERS GP, L.L.C.. This page lists 84 institutional shareholders reporting positions in this security for the Q4 2021 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

Q4 2021 holders

Holder diff

-8

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 Value $	Q4 2021 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.