SYNLOGIC, INC. - Common Stock, par value $0.001 per share (SYBX) Institutional Ownership

13F Institutional Holders and Ownership History from Q3 2023 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.001 per share
Symbol
SYBX on Nasdaq
Shares outstanding
11,818,182
Price per share
$1.11
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
6,655,293
Total reported value
$11,108,525
% of total 13F portfolios
0%
Share change
-116,582
Value change
-$178,424
Number of holders
23
Price from insider filings
$1.11
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of SYNLOGIC, INC. - Common Stock, par value $0.001 per share (SYBX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Radoff Bradley Louis 4.4% $894,400 520,000 Radoff Bradley Louis 30 Sep 2025

As of 30 Sep 2025, 23 institutional investors reported holding 6,655,293 shares of SYNLOGIC, INC. - Common Stock, par value $0.001 per share (SYBX). This represents 56% of the company’s total 11,818,182 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of SYNLOGIC, INC. - Common Stock, par value $0.001 per share (SYBX) together control 56% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Cable Car Capital, LP 28% 3,312,219 0% 2.4% $5,524,781
NEA Management Company, LLC 25% 2,922,772 0% 0.27% $4,875,184
VANGUARD GROUP INC 1.7% 196,461 +7.4% 0% $332,019
GEODE CAPITAL MANAGEMENT, LLC 0.57% 67,665 +2.2% 0% $114,362
RENAISSANCE TECHNOLOGIES LLC 0.33% 39,510 +66% 0% $65,904
CITADEL ADVISORS LLC 0.25% 29,011 0% $49,029
Ikarian Capital, LLC 0.17% 20,422 0% 0.01% $34,513
BlackRock, Inc. 0.17% 19,757 0% 0% $32,955
NORTHERN TRUST CORP 0.16% 19,469 0% $32,474
XTX Topco Ltd 0.09% 11,173 0% $18,882
STATE STREET CORP 0.09% 10,176 0% 0% $17,197
FMR LLC 0.05% 5,323 -97% 0% $8,996
MORGAN STANLEY 0.01% 1,095 -2.7% 0% $1,826
SBI Securities Co., Ltd. 0% 103 -5.5% 0% $172
BANK OF AMERICA CORP /DE/ 0% 64 -7.2% 0% $107
BNP PARIBAS FINANCIAL MARKETS 0% 24 0% 0% $40
Hilltop National Bank 0% 20 0% 0% $33
JONES FINANCIAL COMPANIES LLLP 0% 20 0% $35
WELLS FARGO & COMPANY/MN 0% 5 0% $8
DANSKE BANK A/S 0% 1 0% 0% $2
CITIGROUP INC 0% 1 0% $2
JPMORGAN CHASE & CO 0% 1 0% 0% $2
BARCLAYS PLC 0% 1 0% $2
Rangeley Capital, LLC 0% 0 -100% $0
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0% 0 -100% $0

Institutional Holders of SYNLOGIC, INC. - Common Stock, par value $0.001 per share (SYBX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 1,053 $1,179 +$1,157 $1.11 2
2025 Q3 6,655,293 $11,108,525 -$178,424 $1.69 23
2025 Q2 6,771,875 $8,600,285 -$10,063 $1.27 19
2025 Q1 6,780,519 $8,407,849 +$20,324 $1.24 18
2024 Q4 6,764,147 $9,456,349 -$88,239 $1.39 17
2024 Q3 6,826,001 $10,170,748 -$168,603 $1.49 16
2024 Q2 6,939,069 $10,408,615 +$22,340 $1.50 17
2024 Q1 6,924,167 $12,394,270 +$1,589,732 $1.79 16
2023 Q4 4,715,822 $18,155,320 -$1,046,769 $3.85 23
2023 Q3 2,378,844 $6,684,705 +$6,627,246 $2.81 25