| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Baselake Partners, LP | 9.7% | $1,265,400 | 1,140,000 | Baselake Partners, LP | 20 Jan 2026 | |||
| Radoff Bradley Louis | 4.4% | $894,400 | 520,000 | Radoff Bradley Louis | 30 Sep 2025 |
As of 31 Dec 2025, 25 institutional investors reported holding 6,879,879 shares of SYNLOGIC, INC. - Common Stock, par value $0.001 per share (SYBX). This represents 59% of the company’s total 11,752,577 outstanding shares.
The largest institutional shareholders of SYNLOGIC, INC. - Common Stock, par value $0.001 per share (SYBX) together control 59% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Cable Car Capital, LP | 28% | 3,312,219 | 0% | 0.23% | $3,709,685 |
| NEA Management Company, LLC | 25% | 2,922,772 | 0% | 0.17% | $3,273,505 |
| VANGUARD GROUP INC | 1.7% | 201,060 | +2.3% | 0% | $225,187 |
| CITADEL ADVISORS LLC | 1.2% | 141,608 | +388% | 0% | $158,601 |
| RENAISSANCE TECHNOLOGIES LLC | 0.73% | 85,627 | +117% | 0% | $95,902 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.61% | 71,645 | +5.9% | 0% | $80,247 |
| DRW Securities, LLC | 0.21% | 24,363 | 0% | $27,286 | |
| Ikarian Capital, LLC | 0.17% | 19,966 | -2.2% | 0% | $22,362 |
| BlackRock, Inc. | 0.17% | 19,757 | 0% | 0% | $22,128 |
| NORTHERN TRUST CORP | 0.17% | 19,469 | 0% | 0% | $21,805 |
| JANE STREET GROUP, LLC | 0.13% | 14,998 | 0% | $16,797 | |
| XTX Topco Ltd | 0.12% | 14,398 | +29% | 0% | $16,126 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.1% | 11,623 | 0% | $13,018 | |
| STATE STREET CORP | 0.09% | 10,176 | 0% | 0% | $11,397 |
| FMR LLC | 0.05% | 5,323 | 0% | 0% | $5,962 |
| UBS Group AG | 0.02% | 2,531 | 0% | $2,835 | |
| MORGAN STANLEY | 0.01% | 1,095 | 0% | 0% | $1,226 |
| FLAGSHIP HARBOR ADVISORS, LLC | 0.01% | 1,033 | 0% | $1,157 | |
| SBI Securities Co., Ltd. | 0% | 103 | 0% | 0% | $115 |
| BANK OF AMERICA CORP /DE/ | 0% | 66 | +3.1% | 0% | $73 |
| BNP PARIBAS FINANCIAL MARKETS | 0% | 24 | 0% | 0% | $27 |
| Hilltop National Bank | 0% | 20 | 0% | 0% | $22 |
| CITIGROUP INC | 0% | 1 | 0% | 0% | $1 |
| DANSKE BANK A/S | 0% | 1 | 0% | 0% | $1 |
| JPMORGAN CHASE & CO | 0% | 1 | 0% | 0% | $1 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 6,879,879 | $7,705,466 | +$251,520 | $1.12 | 25 |
| 2025 Q3 | 6,655,293 | $11,108,525 | -$178,424 | $1.69 | 23 |
| 2025 Q2 | 6,771,875 | $8,600,285 | -$10,063 | $1.27 | 19 |
| 2025 Q1 | 6,780,519 | $8,407,849 | +$20,324 | $1.24 | 18 |
| 2024 Q4 | 6,764,147 | $9,456,349 | -$88,239 | $1.39 | 17 |
| 2024 Q3 | 6,826,001 | $10,170,748 | -$168,603 | $1.49 | 16 |
| 2024 Q2 | 6,939,069 | $10,408,615 | +$22,340 | $1.50 | 17 |
| 2024 Q1 | 6,924,167 | $12,394,270 | +$1,589,732 | $1.79 | 16 |
| 2023 Q4 | 4,715,822 | $18,155,320 | -$1,046,769 | $3.85 | 23 |
| 2023 Q3 | 2,378,844 | $6,684,705 | +$6,627,246 | $2.81 | 25 |