Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK)

CUSIP: 86150R107

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Shares outstanding
58,810,778
Total 13F shares
66,984,195
Share change
+1,536,191
Total reported value
$2,126,072,755
Put/Call ratio
8.1%
Price per share
$31.74
Number of holders
183
Value change
+$58,211,085
Number of buys
96
Number of sells
70

Security key

86150R107

Report period

Q4 2025

Institutions

183

Top holders

10

Top shareholders of STOK - Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
FMR LLC
13D/G 13F
Company
9.8%
5,600,920
$177,773,201 -$40,123,708 31 Dec 2025
BlackRock, Inc.
13F 13D/G
Company
6.8%
from 13D/G
5,987,441
$140,704,869 30 Sep 2025
RTW INVESTMENTS, LP
13F
Company
8.7%
5,123,525
$120,402,838 30 Sep 2025
13F
Lynx1 Capital Management LP
13F
Company
9.2%
5,404,674
$109,881,253 30 Sep 2025
13F
BAKER BROS. ADVISORS LP
13F 13D/G
Company
5.8%
from 13D/G
4,633,838
$108,895,193 30 Sep 2025
Redmile Group, LLC
13F
Company
7.1%
4,175,542
$98,125,237 30 Sep 2025
13F
MORGAN STANLEY
13F 13D/G
Company
6.5%
from 13D/G
3,537,050
$83,120,676 30 Sep 2025
TORONTO DOMINION BANK
13F
Company
5.4%
3,173,258
$74,571,563 30 Sep 2025
13F
VANGUARD GROUP INC
13F
Company
5.4%
3,163,874
$74,351,040 30 Sep 2025
13F
Skorpios Trust
13F 13D/G 3/4/5
Company · Montrago Trustees Ltd · 10%+ Owner
4.1%
from 13D/G
2,256,181
$53,020,254 30 Sep 2025
Siren, L.L.C.
13F
Individual
3.8%
2,247,347
$52,812,655 30 Sep 2025
13F
BVF INC/IL
13F
Company
2.8%
1,657,096
$38,941,756 30 Sep 2025
13F
STATE STREET CORP
13F
Company
2.4%
1,425,873
$33,508,016 30 Sep 2025
13F
Polar Capital Holdings Plc
13F
Company
2.3%
1,323,470
$31,101,545 30 Sep 2025
13F
Point72 Asset Management, L.P.
13F
Company
2.2%
1,306,698
$30,707,403 30 Sep 2025
13F
BlackRock Portfolio Management LLC
13D/G
4.7%
2,550,341
$28,946,115 -$2,192,358 30 Jun 2025
GOLDMAN SACHS GROUP INC
13F
Company
2%
1,150,929
$27,046,832 30 Sep 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
2%
1,147,000
$26,959,632 30 Sep 2025
13F
ROYAL BANK OF CANADA
13F
Company
1.6%
915,785
$21,521,000 30 Sep 2025
13F
Assenagon Asset Management S.A.
13F
Company
1.5%
900,272
$21,156,392 30 Sep 2025
13F
MPM BioImpact LLC
13F
Company
1.3%
789,698
$18,557,903 30 Sep 2025
13F
MARSHALL WACE, LLP
13F
Company
1.3%
768,287
$18,054,745 30 Sep 2025
13F
WELLINGTON MANAGEMENT GROUP LLP
13F
Company
1.3%
737,753
$17,337,197 30 Sep 2025
13F
Opaleye Management Inc.
13F
Company
1.2%
682,017
$16,027,400 30 Sep 2025
13F
DIMENSIONAL FUND ADVISORS LP
13F
Company
1.2%
678,307
$15,946,030 30 Sep 2025
13F
TANG CAPITAL MANAGEMENT LLC
13F
Company
0.85%
500,000
$11,750,000 30 Sep 2025
13F
Erste Asset Management GmbH
13F
Company
0.67%
396,000
$9,793,080 30 Sep 2025
13F
NORTHERN TRUST CORP
13F
Company
0.71%
414,917
$9,750,551 30 Sep 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.69%
402,909
$9,468,362 30 Sep 2025
13F
JANUS HENDERSON GROUP PLC
13F
Company
0.57%
334,481
$7,860,021 30 Sep 2025
13F
UBS Group AG
13F
Company
0.52%
306,037
$7,191,870 30 Sep 2025
13F
Granahan Investment Management, LLC
13F
Company
0.43%
253,899
$5,966,626 30 Sep 2025
13F
Parkman Healthcare Partners LLC
13F
Company
0.43%
250,000
$5,875,000 30 Sep 2025
13F
Rhenman & Partners Asset Management AB
13F
Company
0.43%
250,000
$5,875,000 30 Sep 2025
13F
BANK OF AMERICA CORP /DE/
13F
Company
0.42%
249,451
$5,862,098 30 Sep 2025
13F
Schonfeld Strategic Advisors LLC
13F
Company
0.4%
238,015
$5,593,351 30 Sep 2025
13F
Checkpoint Capital L.P.
13F
Company
0.36%
212,049
$4,983,152 30 Sep 2025
13F
Birchview Capital, LP
13F
Company
0.36%
210,000
$4,935,000 30 Sep 2025
13F
Invesco Ltd.
13F
Company
0.35%
208,075
$4,889,763 30 Sep 2025
13F
DAFNA Capital Management LLC
13F
Company
0.29%
169,791
$3,990,089 30 Sep 2025
13F
GILDER GAGNON HOWE & CO LLC
13F
Company
0.26%
155,166
$3,646,401 30 Sep 2025
13F
FIRST TRUST ADVISORS LP
13F
Company
0.26%
152,299
$3,579,026 30 Sep 2025
13F
Penserra Capital Management LLC
13F
Company
0.26%
150,599
$3,539,000 30 Sep 2025
13F
Susquehanna Portfolio Strategies, LLC
13F
Company
0.21%
126,350
$2,969,225 30 Sep 2025
13F
Bank of New York Mellon Corp
13F
Company
0.2%
120,436
$2,830,247 30 Sep 2025
13F
Informed Momentum Co LLC
13F
Company
0.2%
120,181
$2,778,565 30 Sep 2025
13F
FRANKLIN RESOURCES INC
13F
Company
0.2%
115,833
$2,722,077 30 Sep 2025
13F
BARCLAYS PLC
13F
Company
0.18%
107,723
$2,531,492 30 Sep 2025
13F
Nuveen, LLC
13F
Company
0.18%
105,994
$2,490,860 30 Sep 2025
13F
Palo Alto Investors LP
13F
Company
0.18%
105,427
$2,477,535 30 Sep 2025
13F

Institutional Holders of Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK) as of Q4 2025

As of 31 Dec 2025, Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK) was held by 183 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 66,984,195 shares. The largest 10 holders included FMR LLC, RTW INVESTMENTS, LP, Lynx1 Capital Management LP, BlackRock, Inc., Redmile Group, LLC, MORGAN STANLEY, BAKER BROS. ADVISORS LP, TORONTO DOMINION BANK, VANGUARD GROUP INC, and STATE STREET CORP. This page lists 183 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
151
Q4 2025 holders
183
Holder diff
32
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 Value $ Q4 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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