Security Snapshot

SOLENO THERAPEUTICS INC - COMMON STOCK (SLNO) Institutional Ownership

CUSIP: 834203309

13F Institutional Holders and Ownership History from Q3 2022 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

222

Shares (Excl. Options)

62,208,352

Price

$33.48

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Type / Class
Equity / COMMON STOCK
Symbol
SLNO on Nasdaq
Shares outstanding
51,293,400
Price per share
$52.78
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
62,208,352
Total reported value
$2,080,166,968
% of total 13F portfolios
0.01%
Share change
-3,046,660
Value change
-$135,517,907
Number of holders
222
Price from insider filings
$52.78
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • SLNO - SOLENO THERAPEUTICS INC - COMMON STOCK is tracked under CUSIP 834203309.
  • 222 institutions reported positions in Q1 2026.
  • 11 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 247 to 222 between Q4 2025 and Q1 2026.
  • Reported value moved from $3,006,117,784 to $2,080,166,968.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 222 institutions filings for Q1 2026.

Open SEC Evidence

Security key

834203309

Latest holder period

Q1 2026

13F holders

222

13D/G owners

11

CIK / CUSIP context first

Significant Owners of SOLENO THERAPEUTICS INC - COMMON STOCK (SLNO) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
WELLINGTON MANAGEMENT GROUP LLP 8.6% +40% $232,450,270 +$57,970,095 4,426,781 +33% Wellington Management Group LLP 31 Mar 2026
BlackRock, Inc. 6.9% +23% $118,629,904 +$26,016,415 3,543,296 +28% BlackRock, Inc. 31 Mar 2026
ADAGE CAPITAL PARTNERS GP, L.L.C. 6.4% $204,422,873 2,775,976 Adage Capital Management, L.P. 31 Dec 2024
STATE STREET CORP 5.2% $140,768,913 2,680,802 STATE STREET CORPORATION 31 Mar 2026
Avoro Capital Advisors LLC 4.4% -19% $120,773,000 -$31,506,000 2,300,000 -21% Avoro Capital Advisors LLC 31 Mar 2026
Vivo Opportunity Fund Holdings, L.P. 4.2% -46% $152,178,416 -$115,402,258 2,251,160 -43% Vivo Opportunity Fund Holdings, L.P. 30 Sep 2025
Adage Capital Management, L.P. 2.6% -64% $94,746,538 -$146,988,629 1,401,576 -61% Adage Capital Management, L.P. 30 Sep 2025
JANUS HENDERSON GROUP PLC 2.3% -85% $63,290,461 -$313,644,908 1,205,303 -83% JANUS HENDERSON GROUP PLC 30 Apr 2026
PRICE T ROWE ASSOCIATES INC /MD/ 2% -70% $53,868,329 -$127,895,561 1,025,868 -70% T. Rowe Price Associates, Inc. 31 Mar 2026
Nantahala Capital Management, LLC 2% -60% $86,766,978 -$140,918,982 1,001,350 -62% Nantahala Capital Management, LLC 30 Jun 2025
FMR LLC 0.4% -98% $10,135,145 -$292,764,044 193,014 -97% FMR LLC 30 Apr 2026

As of 31 Mar 2026, 222 institutional investors reported holding 62,208,352 shares of SOLENO THERAPEUTICS INC - COMMON STOCK (SLNO). This represents 121% of the company’s total 51,293,400 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of SOLENO THERAPEUTICS INC - COMMON STOCK (SLNO) together control 88% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
JANUS HENDERSON GROUP PLC 14% 7,099,328 -1.1% 0.11% $237,631,668
FMR LLC 11% 5,788,410 -28% 0.01% $193,795,955
WELLINGTON MANAGEMENT GROUP LLP 8.6% 4,426,781 +33% 0.03% $148,208,627
BlackRock, Inc. 7.3% 3,742,774 -3.3% 0% $125,308,074
STATE STREET CORP 5.2% 2,680,802 +1.2% 0% $89,753,251
Avoro Capital Advisors LLC 4.5% 2,300,000 -21% 0.76% $77,004,000
VANGUARD CAPITAL MANAGEMENT LLC 4.2% 2,153,218 0% 0% $72,089,739
Nantahala Capital Management, LLC 3.4% 1,744,124 +33% 3.6% $58,393,272
Polar Capital Holdings Plc 3.3% 1,698,855 +49% 0.25% $56,877,665
Khrom Capital Management LLC 2.9% 1,511,481 4.6% $50,604,384
GEODE CAPITAL MANAGEMENT, LLC 2.4% 1,237,550 +6.4% 0% $41,440,562
Woodline Partners LP 2.2% 1,112,104 +0.03% 0.14% $37,233,242
Deep Track Capital, LP 2.1% 1,078,710 +7.9% 0.75% $36,115,211
PRICE T ROWE ASSOCIATES INC /MD/ 2% 1,025,937 -69% 0% $34,350,000
BRAIDWELL LP 1.9% 959,259 -19% 1.1% $32,115,991
READYSTATE ASSET MANAGEMENT LP 1.9% 952,165 +8.9% 1.9% $31,878,484
FRANKLIN RESOURCES INC 1.6% 835,178 +1.4% 0.01% $27,961,773
Vestal Point Capital, LP 1.4% 730,000 0.68% $24,440,400
Commodore Capital LP 1.3% 652,432 -46% 1.3% $21,843,423
SCHRODER INVESTMENT MANAGEMENT GROUP 1.3% 648,827 +44% 0.02% $19,750,294
Hood River Capital Management LLC 1.2% 623,421 +0.88% 0.21% $20,872,135
Pictet Asset Management Holding SA 1.2% 616,217 -1.3% 0.02% $20,630,945
MILLENNIUM MANAGEMENT LLC 1.2% 606,513 -51% 0.02% $20,306,055
Catalio Capital Management, LP 1.1% 577,808 +60% 4% $19,345,012
KINGDON CAPITAL MANAGEMENT, L.L.C. 1.1% 575,000 +44% 3.2% $19,251,000

Institutional Holders of SOLENO THERAPEUTICS INC - COMMON STOCK (SLNO) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 62,208,352 $2,080,166,968 -$135,517,907 $33.48 222
2025 Q4 64,916,991 $3,006,117,784 -$193,286,405 $46.30 247
2025 Q3 65,165,847 $4,403,391,909 +$507,196,048 $67.60 237
2025 Q2 56,749,470 $4,754,316,405 +$213,454,357 $83.78 231
2025 Q1 54,568,286 $3,901,554,193 +$304,734,926 $71.45 215
2024 Q4 51,039,620 $2,293,782,533 +$169,954,638 $44.95 164
2024 Q3 47,119,847 $2,378,750,710 +$200,292,187 $50.49 140
2024 Q2 43,315,547 $1,767,618,917 +$339,170,617 $40.80 112
2024 Q1 34,986,278 $1,496,099,214 +$153,335,358 $42.80 97
2023 Q4 31,409,972 $1,264,282,488 +$428,860,586 $40.25 76
2023 Q3 20,301,195 $598,794,549 +$451,363,927 $29.51 54
2023 Q2 4,852,710 $20,757,863 +$7,837,293 $4.29 22
2023 Q1 3,071,637 $6,538,076 +$3,161,387 $2.14 20
2022 Q4 2,785,956 $5,517,109 +$81,616 $1.98 22
2022 Q3 2,781,988 $4,645,586 +$4,630,000 $1.67 14
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