Silence Therapeutics plc - Ordinary share, nominal value 0.05 GBP per share (SLN)

Q: What does CUSIP 82686Q101 represent in this 13F holders report?

CUSIP 82686Q101 is the security identifier for SLN - Silence Therapeutics plc - Ordinary share, nominal value 0.05 GBP per share used to aggregate holder disclosures.

Q: How many institutions held SLN - Silence Therapeutics plc - Ordinary share, nominal value 0.05 GBP per share in Q4 2021?

21 institutional investors reported SLN - Silence Therapeutics plc - Ordinary share, nominal value 0.05 GBP per share for Q4 2021. Use the holders table for investor-level position and value details.

CUSIP: 82686Q101

Q4 2021 13F Holders as of 31 Dec 2021

Security type / class: Equity / Ordinary share, nominal value 0.05 GBP per share
Total 13F shares: 10,341,285
Total 13F value: $246,622,000
Share change: +7,180,169
SEC-reported price per share: $23.89
Number of holders: 21
Value change: +$171,435,669
Number of buys: 18
Shares outstanding: 141,918,771

Security key

82686Q101

Report period

Q4 2021

Institutions

Top holders

SLN full security history Ownership snapshot Full 13F holder table Silence Therapeutics plc SEC filings Silence Therapeutics plc company facts

Broader feeds

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Ownership snapshot

Top reported holders of SLN - Silence Therapeutics plc - Ordinary share, nominal value 0.05 GBP per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

BVF INC/IL

Disclosed value leader

BVF INC/IL

Comparable rows

7/7

Latest evidence

30 Sep 2021

13F Lead comparable stake: 0.47% Showing 1-6 of 7 holder rows.

Quick read

BVF INC/IL leads the comparable SEC ownership view at 0.47%.

7 of 7 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens BVF INC/IL's linked filing trail.

Comparable ownership Top 5

BVF INC/IL 0.47%

Lombard Odier Asset Management (U... 0.42%

ADAGE CAPITAL PARTNERS GP, L.L.C. 0.31%

Consonance Capital Management LP 0.13%

BLAIR WILLIAM & CO/IL 0.03%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 7 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
BVF INC/IL	13F Company 13F	0.47%	$14,413,000 666,666 shares	—	30 Sep 2021
Lombard Odier Asset Management (USA) Corp	13F Company 13F	0.42%	$10,653,000 598,141 shares	—	30 Sep 2021
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F Company 13F	0.31%	$9,160,000 444,444 shares	—	30 Sep 2021
Consonance Capital Management LP	13F Company 13F	0.13%	$3,729,000 178,787 shares	—	30 Sep 2021
BLAIR WILLIAM & CO/IL	13F Company 13F	0.03%	$911,000 44,444 shares	—	30 Sep 2021
SG Americas Securities, LLC	13F Company 13F	0.01%	$275,000 12,702 shares	—	30 Sep 2021

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2021

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

10,341,285

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

Q4 2021 holders

Holder diff

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 value	Q4 2021 value	Value change	Value Chg %