Security Snapshot

Seaport Therapeutics, Inc. - Voting Common Stock, $0.001 par value per share (SPTX) Institutional Ownership

CUSIP: 81221K108

13F Institutional Holders and Ownership History for Q2 2026

Latest Period

Q2 2026

Institutions Reporting

54

Shares (Excl. Options)

37,408,896

Price

$21.72

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
+37,408,896
Value change
+$813,850,806
Number of holders
54
Issuer context Names, identifiers, and filing context for this profile. 2 identity fields
Shares outstanding
53,477,606
SEC-reported price per share
$23.80
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • SPTX - Seaport Therapeutics, Inc. - Voting Common Stock, $0.001 par value per share is tracked under CUSIP 81221K108.
  • 54 institutions reported positions in Q2 2026.
  • 3 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Latest quarter on this page is Q2 2026.
  • Additional quarter-over-quarter change detail appears as history expands.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 54 institutions filings for Q2 2026.

Open SEC evidence

Security key

81221K108

Latest holder period

Q2 2026

13F holders

54

13D/G owners

3

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
3
Security
SPTX
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
PureTech LYT, Inc. 31% $335,368,761 16,685,013 PureTech Health plc 30 Jun 2026
Zohar Daphne 9.1% $105,032,490 5,225,497 Zohar Daphne 30 Jun 2026
PAUL STEVEN M 6.3% $70,686,032 3,516,718 PAUL STEVEN M 30 Jun 2026

As of 30 Jun 2026, 54 institutional investors reported holding 37,408,896 shares of Seaport Therapeutics, Inc. - Voting Common Stock, $0.001 par value per share (SPTX). This represents 70% of the company’s total 53,477,606 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
68%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
ARCH Venture Management, LLC 12% 6,294,951 12% $136,600,437
GENERAL ATLANTIC, L.P. 11% 6,101,582 4.6% $132,526,361
Sofinnova Investments, Inc. 6.7% 3,564,871 4.1% $77,428,998
GOLDMAN SACHS GROUP INC 4.1% 2,178,642 0% $47,320,104
TRV GP VI, LLC 3.9% 2,061,222 19% $44,769,742
CANADA PENSION PLAN INVESTMENT BOARD 3.7% 1,975,791 0.02% $42,914,181
JPMORGAN CHASE & CO 3.4% 1,815,845 0% $40,892,829
Foresite Capital Management VI LLC 3.3% 1,779,521 6% $38,651,196
PRICE T ROWE ASSOCIATES INC /MD/ 2.4% 1,308,604 0% $28,424,000
FMR LLC 2.2% 1,185,100 0% $25,740,372
Bellevue Group AG 2.1% 1,100,000 0.5% $23,892,000
Siren, L.L.C. 2% 1,095,316 0.48% $23,790,264
JENNISON ASSOCIATES LLC 2% 1,079,669 0.01% $23,450,411
RA CAPITAL MANAGEMENT, L.P. 1.3% 700,000 0.13% $15,204,000
VANGUARD CAPITAL MANAGEMENT LLC 1.1% 599,217 0% $13,014,993
Woodline Partners LP 1.1% 586,345 0.04% $12,735,413
PERCEPTIVE ADVISORS LLC 0.93% 500,000 0.17% $10,860,000
BRAIDWELL LP 0.93% 500,000 0.4% $10,860,000
PRINCIPAL FINANCIAL GROUP INC 0.78% 414,672 0% $9,006,677
Aberdeen Group plc 0.58% 310,355 0.01% $6,740,911
UBS Group AG 0.52% 279,184 0% $6,063,876
BlackRock, Inc. 0.43% 229,863 0% $4,992,624
SEVEN GRAND MANAGERS, LLC 0.42% 225,000 0.2% $4,887,000
CITADEL ADVISORS LLC 0.36% 191,144 0% $4,151,648
GEODE CAPITAL MANAGEMENT, LLC 0.33% 175,866 0% $3,821,843

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
1
Latest
Q2 2026
Rows shown
1-1 of 1
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 37,408,896 $813,850,806 +$813,850,806 $21.72 54
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