SCYNEXIS INC - Common Stock, par value $0.001 per share (SCYX) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2016 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.001 per share
Symbol
SCYX on Nasdaq
Shares outstanding
44,712,778
Price per share
$0.80
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
8,659,253
Total reported value
$5,473,885
% of total 13F portfolios
0%
Share change
-2,865,397
Value change
-$2,367,157
Number of holders
35
Price from insider filings
$0.80
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of SCYNEXIS INC - Common Stock, par value $0.001 per share (SCYX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Avidity Partners Management LP 9.9% 0% $2,921,533 -$59,527 4,426,565 -2% Avidity Partners Management LP 31 Dec 2025
FEDERATED HERMES, INC. 8.4% -26% $2,367,278 -$1,060,843 3,533,250 -31% Federated Hermes, Inc. 31 Dec 2025

As of 31 Dec 2025, 35 institutional investors reported holding 8,659,253 shares of SCYNEXIS INC - Common Stock, par value $0.001 per share (SCYX). This represents 19% of the company’s total 44,712,778 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of SCYNEXIS INC - Common Stock, par value $0.001 per share (SCYX) together control 19% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Avidity Partners Management LP 4.7% 2,081,660 -38% 0.38% $1,316,442
GOLDMAN SACHS GROUP INC 4.4% 1,984,561 0% $1,255,036
VANGUARD GROUP INC 3.9% 1,762,322 0% 0% $1,113,787
ACADIAN ASSET MANAGEMENT LLC 1.3% 583,114 +40% 0% $367,000
GEODE CAPITAL MANAGEMENT, LLC 1% 449,223 +7.1% 0% $284,145
BlackRock, Inc. 0.75% 334,648 0% 0% $211,631
Yakira Capital Management, Inc. 0.42% 189,802 0% 0.04% $120,031
RENAISSANCE TECHNOLOGIES LLC 0.39% 176,000 +0.8% 0% $111,302
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.37% 163,937 0% 0% $103,674
GSA CAPITAL PARTNERS LLP 0.36% 160,983 +54% 0.01% $102,000
STATE STREET CORP 0.27% 120,730 0% 0% $76,350
CITADEL ADVISORS LLC 0.23% 103,933 0% $65,727
WEALTH EFFECTS LLC 0.2% 91,500 -8% 0.02% $57,865
Nierenberg Investment Management Company, LLC 0.17% 75,555 0% 0.02% $47,781
NORTHERN TRUST CORP 0.17% 75,454 +68% 0% $47,717
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.11% 51,015 0% $32,262
LPL Financial LLC 0.11% 47,980 -11% 0% $30,343
MORGAN STANLEY 0.1% 46,095 +194% 0% $29,150
Bank of New York Mellon Corp 0.08% 35,058 -0% 0% $22,171
RAYMOND JAMES FINANCIAL INC 0.07% 33,395 +55% 0% $21,119
UBS Group AG 0.05% 23,533 -55% 0% $14,873
PDS Planning, Inc 0.03% 15,000 0% 0% $9,486
JANE STREET GROUP, LLC 0.03% 14,892 0% $9,418
Creative Planning 0.03% 12,633 +23% 0% $7,989
Pingora Partners LLC 0.03% 12,000 0% 0% $7,589

Institutional Holders of SCYNEXIS INC - Common Stock, par value $0.001 per share (SCYX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 8,659,253 $5,473,885 -$2,367,157 $0.63 35
2025 Q3 11,770,589 $9,062,084 +$525,519 $0.77 39
2025 Q2 11,104,736 $7,491,656 -$375,330 $0.67 38
2025 Q1 11,607,170 $11,048,844 -$545,861 $0.95 39
2024 Q4 12,084,115 $14,620,933 -$1,441,564 $1.21 46
2024 Q3 13,162,025 $19,610,662 -$1,197,150 $1.49 41
2024 Q2 13,879,344 $27,759,844 -$1,642,838 $2.00 52
2024 Q1 14,768,254 $21,713,651 -$3,163,740 $1.47 52
2023 Q4 16,513,253 $36,804,059 -$159,323 $2.23 51
2023 Q3 16,565,934 $37,768,462 -$2,169,520 $2.28 59
2023 Q2 17,376,537 $51,256,899 +$10,377,755 $2.95 49
2023 Q1 13,826,672 $41,474,216 -$95,646 $3.00 52
2022 Q4 15,328,373 $23,912,315 -$2,080,852 $1.56 39
2022 Q3 16,296,834 $39,099,000 +$50,938 $2.40 41
2022 Q2 16,276,075 $30,420,000 +$3,854,940 $1.86 38
2022 Q1 14,013,914 $54,788,775 -$6,178,432 $3.91 43
2021 Q4 14,998,291 $91,491,250 +$28,859,111 $6.10 44
2021 Q3 10,189,327 $54,081,250 -$6,945,604 $5.30 40
2021 Q2 11,423,587 $84,077,000 +$21,892,357 $7.36 42
2021 Q1 8,426,492 $66,908,026 -$17,961,441 $7.94 39
2020 Q4 10,838,141 $82,910,000 +$51,367,527 $7.65 39
2020 Q3 4,038,400 $17,809,000 +$17,809,000 $4.41 25
2020 Q2 660 $5,000 $7.58 1
2020 Q1 660 $5,000 $7.58 1
2019 Q4 660 $5,000 $7.58 1
2019 Q3 660 $5,000 $7.58 1
2019 Q2 660 $5,000 $7.58 1
2019 Q1 660 $5,000 $7.58 1
2017 Q1 0 $0 -$10,000 $0.80 0
2016 Q4 3,000 $10,000 $3.33 1
2016 Q3 3,000 $12,000 $4.00 1
2016 Q2 3,000 $7,000 +$7,000 $2.33 1