Security key
76155X100
CUSIP: 76155X100
Security key
76155X100
Report period
Q4 2025
Institutions
385
Top holders
10
Broader feeds
Reporting periods
Recent filing periods:
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Farallon Capital Partners, L.P. |
13D/G
|
Dapice Joshua J. |
7.5%
|
14,596,149
|
$1,499,170,464 | +$137,025,822 | 31 Dec 2025 | |
| FMR LLC |
13F
13D/G
|
Company |
5%
from 13D/G
|
9,401,687
|
$439,058,770 | — | 30 Sep 2025 | |
| BAKER BROS. ADVISORS LP |
13D/G
13F
|
Company |
4.9%
|
9,455,357
|
$971,159,717 | +$9,283,443 | 31 Dec 2025 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
4.5%
from 13D/G
|
8,327,758
|
$388,906,300 | — | 30 Sep 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
13F
|
Company |
3.6%
|
6,987,639
|
$717,700,402 | -$336,077,288 | 31 Dec 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
7.9%
|
15,663,094
|
$731,466,490 | — | 30 Sep 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
5.7%
|
11,356,054
|
$530,307,153 | — | 30 Sep 2025 | |
| Nextech Invest, Ltd. |
13F
|
Company |
3.8%
|
7,601,087
|
$354,970,763 | — | 30 Sep 2025 | |
| Paradigm Biocapital Advisors LP |
13F
|
Company |
3.1%
|
6,223,291
|
$290,627,690 | — | 30 Sep 2025 | |
| Bellevue Group AG |
13F
|
Company |
2.8%
|
5,573,838
|
$260,298,235 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.6%
|
5,254,639
|
$245,391,641 | — | 30 Sep 2025 | |
| T. Rowe Price Investment Management, Inc. |
13F
|
Company |
2.4%
|
4,782,318
|
$223,335,000 | — | 30 Sep 2025 | |
| Alphabet Inc. |
13F
|
Company |
2.1%
|
4,133,277
|
$193,024,036 | — | 30 Sep 2025 | |
| BVF INC/IL |
13F
|
Company |
2%
|
3,974,913
|
$185,628,437 | — | 30 Sep 2025 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. |
13F
|
Company |
1.8%
|
3,650,342
|
$170,470,971 | — | 30 Sep 2025 | |
| Holocene Advisors, LP |
13F
|
Company |
1.7%
|
3,437,283
|
$160,521,116 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.6%
|
3,145,640
|
$146,932,051 | — | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
1.5%
|
2,915,883
|
$136,171,736 | — | 30 Sep 2025 | |
| a16z Capital Management, L.L.C. |
13F
|
Company |
1.4%
|
2,748,523
|
$128,356,024 | — | 30 Sep 2025 | |
| Casdin Capital, LLC |
13F
|
Company |
1.3%
|
2,647,333
|
$123,630,451 | — | 30 Sep 2025 | |
| WESTFIELD CAPITAL MANAGEMENT CO LP |
13F
|
Company |
1.3%
|
2,513,967
|
$117,402,259 | — | 30 Sep 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
1.3%
|
2,498,327
|
$116,671,883 | — | 30 Sep 2025 | |
| GENERAL ATLANTIC, L.P. |
13F
|
Company |
1.2%
|
2,474,428
|
$115,555,788 | — | 30 Sep 2025 | |
| Logos Global Management LP |
13F
|
Company |
0.88%
|
1,750,000
|
$81,725,000 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.82%
|
1,635,395
|
$76,372,947 | — | 30 Sep 2025 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
0.72%
|
1,440,818
|
$67,276,999 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.72%
|
1,434,642
|
$66,997,809 | — | 30 Sep 2025 | |
| Rock Springs Capital Management LP |
13F
|
Company |
0.67%
|
1,335,270
|
$62,357,109 | — | 30 Sep 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.66%
|
1,311,741
|
$61,189,778 | — | 30 Sep 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.61%
|
1,224,759
|
$57,196,309 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.59%
|
1,180,085
|
$55,109,970 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
0.55%
|
1,088,965
|
$50,854,666 | — | 30 Sep 2025 | |
| Caligan Partners LP |
13F
|
Company |
0.53%
|
1,064,249
|
$49,700,428 | — | 30 Sep 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
0.52%
|
1,043,720
|
$48,741,724 | — | 30 Sep 2025 | |
| Frazier Life Sciences Management, L.P. |
13F
|
Company |
0.5%
|
997,455
|
$46,581,149 | — | 30 Sep 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.48%
|
951,490
|
$44,434,581 | — | 30 Sep 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
0.47%
|
928,123
|
$43,343,344 | — | 30 Sep 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.44%
|
868,724
|
$40,569,411 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.43%
|
859,548
|
$40,140,892 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.38%
|
753,867
|
$35,205,590 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.37%
|
738,026
|
$34,465,815 | — | 30 Sep 2025 | |
| DAFNA Capital Management LLC |
13F
|
Company |
0.33%
|
657,176
|
$30,690,119 | — | 30 Sep 2025 | |
| First Turn Management, LLC |
13F
|
Company |
0.32%
|
643,050
|
$30,030,435 | — | 30 Sep 2025 | |
| Vestal Point Capital, LP |
13F
|
Company |
0.32%
|
630,000
|
$29,421,000 | — | 30 Sep 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.3%
|
597,455
|
$27,901,149 | — | 30 Sep 2025 | |
| EVENTIDE ASSET MANAGEMENT, LLC |
13F
|
Company |
0.3%
|
595,038
|
$27,788,217 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.27%
|
529,270
|
$24,716,928 | — | 30 Sep 2025 | |
| MIC Capital Management UK LLP |
13F
|
Company |
0.26%
|
508,569
|
$23,750,172 | — | 30 Sep 2025 | |
| Checkpoint Capital L.P. |
13F
|
Company |
0.25%
|
492,300
|
$22,990,410 | — | 30 Sep 2025 | |
| COMERICA BANK |
13F
|
Company |
0.25%
|
490,216
|
$22,893,059 | — | 30 Sep 2025 |
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).